Josh Michener

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Josh Michener


  • 1st year Bioengineering grad student at Caltech
  • S.B. 2006, Chemical Engineering and Biology at MIT

Lab history

  • Grad student in the Smolke Lab at Caltech.
  • Rotated in the Smolke, Arnold, and Elowitz labs at Caltech
  • UROP in the Endy Lab at MIT, January 2005 - January 2006.

Contact Info

Josh Michener
1200 E. California Blvd.
MC 138-78
Pasadena, CA, 91125


My research focuses on applying RNA switches, developed elsewhere in the lab, to provide dynamic control of enzymatic pathways. Specifically, I am using those switches to construct feedback control systems, with the goal of producing a predictable output despite variations in reaction conditions. These control systems can then be used in metabolic engineering to change both the transient and equilibrium responses of a pathway.

Past Projects

  • Development of an in vivo screen for synthetic riboswitches.
  • Design and construction of a screening plasmid to measure the PoPS transfer curve of a BioBricks device.

Interesting papers

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