Difference between revisions of "Javidlab"

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'''Room 4-304 Biotech Building'''<br>
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'''School of Medicine, Tsinghua University'''<br>
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[[Javidlab | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Home''' </font>]] &nbsp;&nbsp;&nbsp;
 
[[Javidlab:research | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Research''' </font>]] &nbsp;&nbsp;&nbsp;
 
[[Javidlab:publications | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Publications''' </font>]] &nbsp;&nbsp;&nbsp;
 
[[Javidlab:labmembers | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Lab Members''' </font>]] &nbsp;&nbsp;&nbsp;
 
[[Javidlab:labalumni | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Lab Alumni''' </font>]] &nbsp;&nbsp;&nbsp;
 
[[Javidlab:funstuff | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Fun Stuff''' </font>]]&nbsp;&nbsp;&nbsp;
 
[[Javidlab:contact | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Contact''' </font>]]
 
  
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[[Javidlab | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''HOME''' </font>]]
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[[Javidlab:news | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''NEWS''' </font>]]
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[[Javidlab:research | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Research''' </font>]]
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[[Javidlab:publications | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Publication''' </font>]]
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[[Javidlab:labmembers | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Members''' </font>]]
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[[Javidlab:labalumni | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Alumni''' </font>]]
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[[Javidlab:funstuff | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Fun''' </font>]]
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[[Javidlab:contact | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Contact''' </font>]]
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<font face="trebuchet ms" size=5 style="color:#930000">
 
MAIN<br>
 
TOPIC<br>
 
</font>
 
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1. 'Adaptive mistranslation'<br>
 
2. Mycobacteria and host-pathogen interactions<br>
 
3. Protein translation fidelity<br>
 
4. GatCAB dependent tRNA synthesis and protein evolution<br>
 
<br>
 
'''<<<<<<<<< '''<br>
 
<font size="1"; color="#930000">
 
Scanning electron micrograph of Mycobacterium tuberculosis bacteria, which cause TB. <br>
 
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Credit: NIAID<br>
 
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<font face="trebuchet ms" size=6 style="color:#000079"><br>RESEARCH INTEREST<br></font>
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<br>
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The Javid lab principal interest is in mycobacterial pathophysiology. Here are some of research interests:<br><br>
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<font face="calibri" size="4">'''1. 'Adaptive mistranslation''''</font><br>
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<font face="calibri" size="4">'''2. Mycobacteria and host-pathogen interactions'''</font><br>
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<font face="calibri" size="4">'''3. Protein translation fidelity'''</font><br>
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<font face="calibri" size="4">'''4. GatCAB dependent tRNA synthesis and protein evolution'''</font><br><br>
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<font style="color:#000079"> Undergraduate and graduate students, as well as post-doctoral scientists, interested in our work should contact Dr. Javid directly.  (email: ''bjavid{at}gmail.com'') </font>
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RESEARCH INTEREST<br>
 
 
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The Javid lab principal interest is in mycobacterial pathophysiology. Tuberculosis causes more infectious disease deaths in China than any other pathogen, and the basic biology of its causative organism,Mycobacterium tuberculosis is still poorly understood.Our lab is interested in how fundamental physiological processes in mycobacteria can influence important clinical phenotypes such as antibiotic tolerance and immune evasion. We have shown that altering the protein translation error rate in mycobacteria can profoundly influence phenotypic resistance to first-line anti-mycobacterial drugs. We are now trying to understand the molecular mechanism and regulation of translational fidelity.Mycobacterium tuberculosis can reside within the host for decades without detection. We are trying to understand how this happens -- at the level of both innate and adaptive immunity.
 
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== >>>>>>>>>>><br> <font face="trebuchet ms" size=2 style="color:#930000"> '''See our members in the LINK below''' </font> ==
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LINK:<br>
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[[Javidlab:labmembers]]
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{{Click || image=THUMTB-news.png | link=Javidlab:news | width=100px | height=100px }}
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== <font face="trebuchet ms" size=2 style="color:#930000"> '''Amaze yourself by seeing the LINK below''' </font> ==
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''Exciting things happen here''
LINK:<br>
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[[Javidlab:research]]
 
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{{Click || image=THUMTB-research.png | link=Javidlab:research | width=100px | height=100px }}
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''I love my research in Javid Lab''
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{{Click || image=THUMTB-members.png | link=Javidlab:labmembers | width=100px | height=100px }}
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''Meet our lovely members''
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{{Click || image=THUMTB-fun.png | link=Javidlab:funstuff | width=100px | height=100px }}
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''Happy Hours''
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Lab name written by Nano Luciferase
 
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== <<<<<<<<<<<<br> <font face="trebuchet ms" size=4 style="color:#930000"> '''Nano Luciferase''' </font> ==
 
Bio_luminescence by Nano Luciferase (Promega), which we optimised to be easily expressed in Mycobacterium, and a novel mistranslation reporter with 100 times higher signal over canonical Renilla luciferase.
 
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Room 4-302 Biotech Building<br>
 
School of Medicine<br>
 
Tsinghua University
 
 
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Latest revision as of 19:27, 9 September 2015



THUMTB-LOGO3.png

Room 4-304 Biotech Building
School of Medicine, Tsinghua University

THU-LOGO.png

HOME

NEWS

Research

Publication

Members

Alumni

Fun

Contact

THUMTB-HOMEGIF3.gif


RESEARCH INTEREST

The Javid lab principal interest is in mycobacterial pathophysiology. Here are some of research interests:

1. 'Adaptive mistranslation'
2. Mycobacteria and host-pathogen interactions
3. Protein translation fidelity
4. GatCAB dependent tRNA synthesis and protein evolution

Undergraduate and graduate students, as well as post-doctoral scientists, interested in our work should contact Dr. Javid directly. (email: bjavid{at}gmail.com)


THUMTB-hotlinks.png

Exciting things happen here

I love my research in Javid Lab

Meet our lovely members

Happy Hours


THUMTB-spin.gif

THUMTB-slogen.png