Difference between revisions of "James P. McDonald Week 5"

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(answered first 3 questions)
(link to sgd pathway)
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*There are 56 pathways listed in the database that L-glutamate participates
 
*There are 56 pathways listed in the database that L-glutamate participates
 
*Pathway
 
*Pathway
**[[http://pathway.yeastgenome.org/YEAST/NEW-IMAGE?type=PATHWAY&object=PWY3O-13|SGD Pathway]]
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**[[http://pathway.yeastgenome.org/YEAST/NEW-IMAGE?type=PATHWAY&object=PWY3O-13 SGD Pathway]]
 
**[[image:SGD_Pathway.jpg]]
 
**[[image:SGD_Pathway.jpg]]
  

Revision as of 22:39, 13 February 2013

Exploring Pathway Databases

Saccharomyces Genome Database

  • GDH2 has a homolog in humans. A deficiency of the human homologs, GLUD1 and GLUD2, has been known to cause hyperinsulinism-hyperammonemia syndrome and various neurological disorders.
  • Gene Expression Regulation:
    • GDH1: expression regulated by nitrogen and carbon sources
    • GDH3: expression regulated by nitrogen and carbon sources
    • GDH2: expression sensitive to nitrogen catabolite repression and intracellular ammonia levels
    • GLN1: expression regulated by nitrogen source and amino acid limitation
    • GLT1: expression regulated by nitrogen source
  • There are 56 pathways listed in the database that L-glutamate participates
  • Pathway

KEGG

Reactome

Class Links

Journal Entries and Assignments