Jacobs

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Welcome to the Cell and Molecular Biomechanics Lab at Columbia University! The CMBL is focused on determining the mechanism that allows cells to sense and respond to extracellular mechanical stimulation. Particularly we are interested in determining, at a cellular level, how bone tissue is regulated by physical loading. This work has applications in developing new therapies to age-related bone loss and osteoporosis. We explore this question both in cell culture identifying novel molecular targets and in quantifying the skeletal sensitivity to loading of tissue-specific conditional deletions in mice. Our current targets include focal adhesions, cytoskeletal proteins, and the cell's primary cilium.

Recent updates to the lab wiki

15 December 2017

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Experimental Anaesthesiology Antkowiak Lab:Theses‎‎ (2 changes | history) . . (+89). . [Berthold Drexler‎ (2×)]

     

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     05:00  Experimental Anaesthesiology Antkowiak Lab:Publications‎ (diff | hist) . . (+239). . Berthold Drexler (talk | contribs) (2017)
     04:05  Hexlab:Lab Members‎ (diff | hist) . . (+2). . Ximiao He (talk | contribs)

14 December 2017

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     15:39  User:Maria Clara T Astolfi‎ (diff | hist) . . (-886). . Maria Clara T Astolfi (talk | contribs) (News from our Genetic Circuits Regulation Group)
     12:01  Qin‎ (diff | hist) . . (+114). . Lixitong (talk | contribs) (News)
     11:07  User:Lonelybuffalo‎ (diff | hist) . . (+191). . Maureen E. Hoatlin (talk | contribs) (week 10 December 12 2017 - Nucleic acid detection with CRISPR-Cas13a/C2c2)
     11:05  User:Helmse‎ (diff | hist) . . (+55). . Maureen E. Hoatlin (talk | contribs) (Paper: "sherlock investigating pathogens")
     11:02  User:Carusob‎ (diff | hist) . . (+103). . Maureen E. Hoatlin (talk | contribs) (Nucleic Acid Detection with CRISPR-Cas13a/c2c2 [http://dx.doi.org/10.1126/science.aam9321])
     11:00  User:Weinjule‎ (diff | hist) . . (+110). . Maureen E. Hoatlin (talk | contribs) (Week 11)
     10:59  User:Guzmanga‎ (diff | hist) . . (+264). . Maureen E. Hoatlin (talk | contribs)

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User:Madeline.churchill‎‎ (2 changes | history) . . (+695). . [Maureen E. Hoatlin‎; Madeline.churchill‎]

     

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(cur | prev) . . (+22). . Maureen E. Hoatlin (talk | contribs) (Nucleic Acid Detection with CRISPR-Cas13a/C2c2)

     

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(cur | prev) . . (+673). . Madeline.churchill (talk | contribs) (Madeline Churchill's Discussion Page)

     10:52 (Upload log) . . Madeline.churchill (talk | contribs) uploaded File:Fenris.JPG
     09:46 (Deletion log) . . Yar (talk | contribs) deleted page OpenWetWare:Privacy policy(Spam: content was: " == İSTANBUL ESCORT HİZMETİ CEYLAN == İstanbul bayan escort Ceylan'ın sesi de baya güzeldi. Ve sürekli escort arkadaşl...", and the only contributor was "Argeles34" ([[User talk:Argeles3...)
     09:45 (Block log) . . Yar (talk | contribs) blocked Argeles34 (talk | contribs) with an expiration time of indefinite (account creation disabled, email disabled, cannot edit own talk page) ‎(Spamming links to external sites)

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[Yar‎ (5×)]

     

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. . User account Lixitong (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

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. . User account Softmatterchem (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

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. . User account Weihuachen (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

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. . User account Tim Springston (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

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. . User account GE Laura (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     07:31  Screencasts of Repeating McGurk Experiments‎ (diff | hist) . . (0). . Ksmith (talk | contribs)
 m   06:45  User:Richard J. Abbott‎ (diff | hist) . . (+70). . Richard J. Abbott (talk | contribs) (Publications)

13 December 2017

     22:13  User:Weinjule‎ (diff | hist) . . (+695). . Weinjule (talk | contribs)
     21:01  Hoatlin:BMB seminar series 2017-2018‎ (diff | hist) . . (+64). . Maureen E. Hoatlin (talk | contribs) (Seminar Schedule 2017-2018)
     19:40  Yeo lab:Lab Members‎ (diff | hist) . . (+75). . Yoonyeo (talk | contribs) (Lab photo archive)
     17:12  User:Lonelybuffalo‎ (diff | hist) . . (+167). . Lonelybuffalo (talk | contribs) (week 10 December 12 2017 - Nucleic acid detection with CRISPR-Cas13a/C2c2)

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Screencasts of Repeating McGurk Experiments‎‎ (12 changes | history) . . (+88). . [Ksmith‎ (12×)]

     

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(cur | prev) . . (+3). . Ksmith (talk | contribs) (Experiment 1:)

     

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     12:35 (Upload log) . . Ksmith (talk | contribs) uploaded File:McGurk Experiment 3.png

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(cur | prev) . . (+513). . Tyler R. Kartzinel (talk | contribs) (Lab Safety)

     

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