Difference between revisions of "IGEM:PennState/2008"

From OpenWetWare
Jump to: navigation, search
m
m
Line 6: Line 6:
 
[[Image:PSUiGEM2007OldMain.jpg]]
 
[[Image:PSUiGEM2007OldMain.jpg]]
  
<font color="#FFFFFF">
+
 
 +
<div style="color: #fff">
 +
<h2>What iGEM is All About</h2>
 
<p>The International Genetically Engineered Machines (iGEM) Competition is an annual undergraduate research competition hosted by MIT.  The project aim is to develop Synthetic Biology through the creation of an open registry of parts, or biobricks. Each part in the registry is an analyzed strain of DNA with several specific restriction sites at each end of the fragment. These strains can be anything from promoters to genes, allowing easy assembly and reassembly of these parts into genetic circuits. The [[http://parts.mit.edu/igem07/index.php/Main_Page| 2007 Jamboree]] consisted of 54 teams from 19 countries who presented their findings.</p>
 
<p>The International Genetically Engineered Machines (iGEM) Competition is an annual undergraduate research competition hosted by MIT.  The project aim is to develop Synthetic Biology through the creation of an open registry of parts, or biobricks. Each part in the registry is an analyzed strain of DNA with several specific restriction sites at each end of the fragment. These strains can be anything from promoters to genes, allowing easy assembly and reassembly of these parts into genetic circuits. The [[http://parts.mit.edu/igem07/index.php/Main_Page| 2007 Jamboree]] consisted of 54 teams from 19 countries who presented their findings.</p>
<h2 style="color: #fff">Our 2007 project: Abstract</h2>
+
<h2 style="color: #fff">Penn State's 2007 iGEM project: Diauxie Elimination</h2>
 
<p>Increasing energy demands have brought about the need for a renewable, efficient energy source.  Using microorganisms to convert biomass to fuel offers a promising alternative to traditional energy sources, but still faces developmental challenges. Microbes such as Escherichia coli have evolved to preferentially metabolize sugars in a process knows as diauxie.  Engineering bacteria to eliminate diauxie with the common lignocellulose sugar xylose would allow faster digestion of ordinary plant biomass while simultaneously reducing the costly sugar residues of wild type bacterial digests.  Such modified strains of E. coli need to reduce or eliminate glucose’s repression of catabolization proteins necessary to utilize the energy stored in xylose.  The effect of such augmentation would be readily assayed with fluorescent proteins placed downstream of xylose regulatory regions.</p>  
 
<p>Increasing energy demands have brought about the need for a renewable, efficient energy source.  Using microorganisms to convert biomass to fuel offers a promising alternative to traditional energy sources, but still faces developmental challenges. Microbes such as Escherichia coli have evolved to preferentially metabolize sugars in a process knows as diauxie.  Engineering bacteria to eliminate diauxie with the common lignocellulose sugar xylose would allow faster digestion of ordinary plant biomass while simultaneously reducing the costly sugar residues of wild type bacterial digests.  Such modified strains of E. coli need to reduce or eliminate glucose’s repression of catabolization proteins necessary to utilize the energy stored in xylose.  The effect of such augmentation would be readily assayed with fluorescent proteins placed downstream of xylose regulatory regions.</p>  
 
<p>If you are interested in joining the team [[IGEM:PennState/Newmember|click here]].</p></font>
 
<p>If you are interested in joining the team [[IGEM:PennState/Newmember|click here]].</p></font>

Revision as of 12:17, 19 May 2008

Psuigemlogo2008.jpg

PSUiGEM2007OldMain.jpg


What iGEM is All About

The International Genetically Engineered Machines (iGEM) Competition is an annual undergraduate research competition hosted by MIT. The project aim is to develop Synthetic Biology through the creation of an open registry of parts, or biobricks. Each part in the registry is an analyzed strain of DNA with several specific restriction sites at each end of the fragment. These strains can be anything from promoters to genes, allowing easy assembly and reassembly of these parts into genetic circuits. The [2007 Jamboree] consisted of 54 teams from 19 countries who presented their findings.

Penn State's 2007 iGEM project: Diauxie Elimination

Increasing energy demands have brought about the need for a renewable, efficient energy source. Using microorganisms to convert biomass to fuel offers a promising alternative to traditional energy sources, but still faces developmental challenges. Microbes such as Escherichia coli have evolved to preferentially metabolize sugars in a process knows as diauxie. Engineering bacteria to eliminate diauxie with the common lignocellulose sugar xylose would allow faster digestion of ordinary plant biomass while simultaneously reducing the costly sugar residues of wild type bacterial digests. Such modified strains of E. coli need to reduce or eliminate glucose’s repression of catabolization proteins necessary to utilize the energy stored in xylose. The effect of such augmentation would be readily assayed with fluorescent proteins placed downstream of xylose regulatory regions.

If you are interested in joining the team click here.

</font>

<html><blink>></blink></html>People

Fulltime Undergraduates

Affiliated Undergraduates

Graduate Students

Faculty


Lab Notebooks

Fun Stuff


<html><a href="http://www2.clustrmaps.com/counter/maps.php?url=http://openwetware.org/wiki/IGEM:PennState&type=small&category=free&clusters=no&map=world" id="clustrMapsLink"><img src="http://www2.clustrmaps.com/counter/index2.php?url=http://openwetware.org/wiki/IGEM:PennState" /></a> <br> <br>

<!-- Start of StatCounter Code --> <script type="text/javascript" language="javascript"> var sc_project=2623386; var sc_invisible=0; var sc_partition=25; var sc_security="dc27ec2c"; </script>

<a href="http://my.statcounter.com/project/standard/stats.php?project_id=2623386&guest=1" id="clustrMapsLink"><img src="http://c26.statcounter.com/counter.php?sc_project=2623386&java=0&security=dc27ec2c&invisible=0" alt="blog counter" border="0"" /></a> <br> <br> <SCRIPT LANGUAGE="JAVASCRIPT"><!-- hide this script tag's contents from old browsers

today = new Date();

BigDay = new Date("November 3, 2007") msPerDay = 24 * 60 * 60 * 1000 ; timeLeft = (BigDay.getTime() - today.getTime()); e_daysLeft = timeLeft / msPerDay; daysLeft = Math.floor(e_daysLeft); e_hrsLeft = (e_daysLeft - daysLeft)*24; hrsLeft = Math.floor(e_hrsLeft); minsLeft = Math.floor((e_hrsLeft - hrsLeft)*60); document.write(<font color=red>"There are only:<BR> <H4>" + daysLeft + " days " + hrsLeft +" hours and " + minsLeft + " minutes left </H4> Until the 2007 iGEM Jamboree! (Nov. 3rd, 2007)<P>"</font>);

// -- done hiding from old browsers --></SCRIPT>

</html>








<html><blink>></blink></html>Project

In The News

Tasks

Protocols

Progress

Background

Links