Difference between revisions of "IGEM:Melbourne/2008/ProjectIdeas"
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== Bacterial TV ==
== Bacterial TV ==
A screen composed of bacteria that release the different colors of fluorescent proteins to form an image.
Revision as of 05:33, 18 December 2007
- 1 Detection of allergens in food
- 2 Biological Circuits
- 3 Biological Manufacturing
- 4 Biological Control
- 5 In vivo sensors, processors and actuators
- 6 cell-cell interaction
- 7 Radiation-proof E.coli
- 8 Gold mining bacteria
- 9 Bacterial desalination
- 10 HIV rapid diagnostic test
- 11 HIV sink
- 12 Remote controlled locomotive micromachine
- 13 Bacterial kettle
- 14 Bacterial TV
Detection of allergens in food
- the presence of certain alergen promote the expression of GFP.
- must be fast reaction. ie. detection on the spot.
- cell-free medium and can be stored in bottles under normal condition.
- variable resistors, capaceitors, a catalog of resistors ...
- setup a basic ALU(arithmetic logic unit), from pre-designed gates
- biological clock; counts up in seconds or minutes (not countdown like peking07-hopcount), something similar but not elegant enough has been done by Harvard2006
- Bacterial cells to assist in production of things like biofuels/fertilisers/etc.
- Cheap and easy production of pharmaceuticals.
In vivo sensors, processors and actuators
Bacteria have remarkable abilities to sense, process and actuate. These attributes of bacteria are potentially useful in designing and fabricating them for therapeutic purposes. One good example is here.  (more...)
- something similar to peking 2007 one..
- group A bacteria undergo conjugation certain number of times before expressing a promotor
- the promotor promotes the expression in group B bacteria of some other protein.
- after undergoing conjugation certain number of times, group B bacteria express a repressor which inhibites the expresion of promotor from group A bacteria thus negative feedback.
- a system with timing and quatity control
- Express the DNA repair system (enzymes) of radiodurans in e.coli ?
Gold mining bacteria
- Bacteria that uptake gold particles in solution possibly using transporters from alfalfa or other plants used in phytomining. For the purpose of making money.
Bacteria that uptake salt from water for the purpose of desalination. Investigations into archaea probably needed.
HIV rapid diagnostic test
A rapid diagnostic test for HIV using bacteria that express CD4 and CCR5 coupled with an amplification signal (such as used in Brown university 2007).
Bacteria that express CD4 and CCR5 to act as a sink within the body thus lowering the viral load of HIV. Immunogenicity must be removed as was done with Bactoblood (UC Berkeley 2007).
Remote controlled locomotive micromachine
A remote control locomotive micro machine using bacterial flagella as the driver. The bacteria with flagella could possibly adhere to the micro machine using adhesins.
Hyperthermophilic bacteria or archaea treated with uncouplers e.g. DNP, used to boil water for power generation.
A television screen composed of bacteria that release the different colors of fluorescent proteins to form an image.