IGEM:Imperial/2010/Modelling: Difference between revisions

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==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Michaelis_Menten Model based on Michaelis Menten Kinetics]==
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Michaelis_Menten Model based on Michaelis Menten Kinetics]==
Comparison between different amplification models (HIV1 and TEV) based on Michaelis Menten kinetics. However, Michaelis Menten kinetics does not apply to our system. Therefore, it had to be modelled from first principle (see below using law of mass action).
Comparison between different amplification models (HIV1 and TEV) based on Michaelis Menten kinetics. However, Michaelis Menten kinetics does not apply to our system. Therefore, it had to be modelled from first principle (see below using law of mass action).
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Mass_Action Model based on Law of Mass Action]==
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Mass_Action Model based on Law of Mass Action]==
Comparison between these 3 different models (which are based on the law of mass action): Simple production, 1-step and 2-step amplification
Comparison between these 3 different models (which are based on the law of mass action): Simple production, 1-step and 2-step amplification
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Variables1 Variables and Constants for this Model]==
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Variables1 Variables and Constants for this Model]==
Here are the variables and constants that are used in the Output Amplification Model.
Here are the variables and constants that are used in the Output Amplification Model.
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=Protein Display Model=
=Protein Display Model=
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Protein_Display Protein Display Model]==
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Protein_Display Protein Display Model]==
This is a model showing when the ComD receptor will be activated (after proteins have been cleaved).
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Variables2 Variables and constants for this Model]==
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Variables2 Variables and constants for this Model]==
Here are the variables and constants that are used in the Protein Display Model.


=Feedback from Wetlab=
=Feedback from Wetlab=
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Experiments1 Experiments for the Output Amplification Model]==  
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Experiments1 Experiments for the Output Amplification Model]==
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Experiments2 Experiments for the Protein Display Model]==
==[http://www.openwetware.org/wiki/IGEM:Imperial/2010/Experiments2 Experiments for the Protein Display Model]==

Revision as of 06:59, 6 September 2010

Objectives

These are our daily objectives.

Output Amplification Model

Model based on Michaelis Menten Kinetics

Comparison between different amplification models (HIV1 and TEV) based on Michaelis Menten kinetics. However, Michaelis Menten kinetics does not apply to our system. Therefore, it had to be modelled from first principle (see below using law of mass action).

Model based on Law of Mass Action

Comparison between these 3 different models (which are based on the law of mass action): Simple production, 1-step and 2-step amplification

Variables and Constants for this Model

Here are the variables and constants that are used in the Output Amplification Model.

Protein Display Model

Protein Display Model

This is a model showing when the ComD receptor will be activated (after proteins have been cleaved).

Variables and constants for this Model

Here are the variables and constants that are used in the Protein Display Model.

Feedback from Wetlab

Experiments for the Output Amplification Model

Experiments for the Protein Display Model