IGEM:Harvard/2006/DNA nanostructures

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Revision as of 18:15, 17 July 2006 by ShawnDouglas (talk | contribs) (Recent Changes)



Project Overview

  • Our goal is to to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
  • The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
  • As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
  • We expect that molecular containers could have several interesting scientific and clinical applications, such as
    • Drug and gene delivery
    • Bio-marker scavenging (early detection of biomarkers)
    • Directed evolution (compartmentalized selections)
    • Using multiplexing for combinatorial chemical synthesis
    • Capture and stabilization of multiprotein complexes
    • Protein folding (chaperones)
    • Cell sorting

Working Team Members

Recent Changes

17 June 2018

     18:38  OpenSourceTB‎ (diff | hist) . . (-905). . Matthew Todd (talk | contribs)
     18:03  OpenSourceTB:Compound Series‎ (diff | hist) . . (+94). . Matthew Todd (talk | contribs)

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15 June 2018

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     07:57  Hoatlin:BMB seminar series 2017-2018‎ (diff | hist) . . (+50). . Millejef (talk | contribs)

14 June 2018

     19:47  X-Lab‎ (diff | hist) . . (+80). . ChanEngr (talk | contribs)

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The Essential Unknowns‎‎ (4 changes | history) . . (+445). . [Koeng‎ (⧼ntimes⧽)]

     

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 m   16:51  User:Korey Griffin‎ (diff | hist) . . (+272). . Korey Griffin (talk | contribs)

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[Yar‎ (⧼ntimes⧽)]

     

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. . User account Millejef (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

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. . User account Advancells (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

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. . User account Thembani (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

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13 June 2018

     18:22  X-Lab‎ (diff | hist) . . (+299). . ChanEngr (talk | contribs)
     17:12  User:JernejTurnsek‎ (diff | hist) . . (-53). . Jernej Turnsek (talk | contribs) (Sports)