Difference between revisions of "IGEM:Harvard/2006/DNA nanostructures"

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==Project Overview==
 
==Project Overview==
*Our goal is to to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
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*Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
 
*The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
 
*The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
 
*As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
 
*As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
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==Working Team Members==
 
==Working Team Members==
*[[User:TChan|Tiffany Chan]] ([[User_talk:TChan|talk]], [[Special:Contributions&target=TChan|edits]])
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*[[User:TChan|Tiffany Chan]] ([[User_talk:TChan|talk]], [[Special:Contributions/TChan|edits]])
*[[User:Kfifer|Katherine Fifer]] ([[User_talk:Kfifer|talk]], [[Special:Contributions&target=Kfifer|edits]])
+
*[[User:Kfifer|Katherine Fifer]] ([[User_talk:Kfifer|talk]], [[Special:Contributions/Kfifer|edits]])
*[[User:Vlau|Valerie Lau]] ([[User_talk:Vlau|talk]], [[Special:Contributions&target=Vlau|edits]])
+
*[[User:Vlau|Valerie Lau]] ([[User_talk:Vlau|talk]], [[Special:Contributions/Vlau|edits]])
*[[User:Matthewmeisel|Matthew Meisel]] ([[User_talk:Matthewmeisel|talk]], [[Special:Contributions&target=Matthewmeisel|edits]])
+
*[[User:Matthewmeisel|Matthew Meisel]] ([[User_talk:Matthewmeisel|talk]], [[Special:Contributions/Matthewmeisel|edits]])
 +
*[[User:Lhahn|Lewis Hahn]] ([[User_talk:Lhahn|talk]], [[Special:Contributions/Lhahn|edits]])
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*TA: [[User:ShawnDouglas|Shawn Douglas]] ([[User_talk:ShawnDouglas|talk]], [[Special:Contributions/ShawnDouglas|edits]])
 +
 
 +
==Recent Changes==
 +
{{Special:Recentchanges/b=IGEM:Harvard/2006/DNA_nanostructures/&limit=20}}

Latest revision as of 18:15, 28 October 2006



Project Overview

  • Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
  • The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
  • As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
  • We expect that molecular containers could have several interesting scientific and clinical applications, such as
    • Drug and gene delivery
    • Bio-marker scavenging (early detection of biomarkers)
    • Directed evolution (compartmentalized selections)
    • Using multiplexing for combinatorial chemical synthesis
    • Capture and stabilization of multiprotein complexes
    • Protein folding (chaperones)
    • Cell sorting

Working Team Members

Recent Changes

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