Difference between revisions of "Hoatlin Lab"

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==Quick Teaching Links==
 
==Quick Teaching Links==
*Our lab's Fanconi Anemia antibodies are available from [http://www.novusbio.com Novus Biologicals]
 
  
[http://openwetware.org/wiki/CANB_610| Advanced Topics in Cancer Biology (CANB 610)]
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*Our lab's Fanconi Anemia antibodies are available from [http://www.novusbio.com Novus Biologicals] and soon by Millipore.
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[http://openwetware.org/wiki/CANB_610 Advanced Topics in Cancer Biology (CANB 610)]
  
 
[[Hoatlin:OHSU_Genetic_Mechanisms_Class| Genetic Mechanisms Class (CON662)]]
 
[[Hoatlin:OHSU_Genetic_Mechanisms_Class| Genetic Mechanisms Class (CON662)]]
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[[Hoatlin:OHSU Replication, Recombination and Repair (R3) Club| OHSU DNA Replication, Recombination and Repair (R3) Club]].
 
[[Hoatlin:OHSU Replication, Recombination and Repair (R3) Club| OHSU DNA Replication, Recombination and Repair (R3) Club]].
  
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[[Hoatlin: CSF|Med Students Cell Structure Function (CSF)]]
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==Classes of the past==
 
[[BMCB625|Advanced Topics in Molecular Biology(BMB625)]]
 
[[BMCB625|Advanced Topics in Molecular Biology(BMB625)]]
 
[[Hoatlin: CSF|Med Students Cell Structure Function (CSF)]]
 
  
 
==Who is Visiting Us?==
 
==Who is Visiting Us?==

Revision as of 11:31, 3 October 2013

Equipped with his five senses, man explores the universe around him and calls the adventure Science.  ~Edwin Powell Hubble, The Nature of Science, 1954

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Lab News

For news, follow the Hoatlin lab Twitter


Our laboratory is interested in understanding the molecular function of the Fanconi anemia (FA) protein network in context with other proteins that regulate or influence genomic stability. Fanconi anemia is a rare genetic disease that is typically associated with developmental abnormalities, bone marrow failure and increased risk of cancer. Because the majority of the FA proteins are unique with no significant homologies, we expect the results of our studies to shed new light on fundamental mechanisms that control the integrity of the human genome and influence cancer susceptibility. The FA pathway is part of a network of proteins that contains BRCA2 and two other recently identified FA genes (FANCN and FANCJ) that influence breast cancer susceptibility. Ultimately, insights into the mechanism of the FA/BRCA network of proteins will lead to an understanding of the underlying molecular defect in FA and may lead to more effective avenues of treatment for this devastating pediatric disease and cancer.

We work in Portland, Oregon at OHSU, in the Department of Biochemistry & Molecular Biology and the OHSU Knight Cancer Institute.

Quick Teaching Links

  • Our lab's Fanconi Anemia antibodies are available from Novus Biologicals and soon by Millipore.

Advanced Topics in Cancer Biology (CANB 610)

Genetic Mechanisms Class (CON662)

OHSU DNA Replication, Recombination and Repair (R3) Club.

Med Students Cell Structure Function (CSF)

Classes of the past

Advanced Topics in Molecular Biology(BMB625)

Who is Visiting Us?

Who's visiting?

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19 April 2018

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     11:26 (Move log) . . Aolsen (talk | contribs) moved page Xromm to XROMM(Acronym looks better in caps)

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     08:40  Taylor:Publications‎ (diff | hist) . . (+18). . Lynne S. Taylor (talk | contribs) (PUBLICATIONS)
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18 April 2018

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BIOL478/S18:Microarray Data Analysis‎‎ (21 changes | history) . . (+7,513). . [Kam D. Dahlquist‎ (21×)]

     

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(cur | prev) . . (-70). . Kam D. Dahlquist (talk | contribs) (Gridding and Generating Intensity Data: remove old Brightspace link)

     

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(cur | prev) . . (+3,072). . Kam D. Dahlquist (talk | contribs) (Identifying regulatory transcription factors responsible for observed changes in gene expression (step 10): paste in protocol from Biomath modeling, modify for HMO1)

     

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(cur | prev) . . (+114). . Kam D. Dahlquist (talk | contribs) (Clustering and GO Term Enrichment with stem (steps 7-8): add section for step 10)

     

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(cur | prev) . . (-751). . Kam D. Dahlquist (talk | contribs) (Clustering and GO Term Enrichment with stem (steps 7-8): delete comment, emphasize to unzip)

     

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(cur | prev) . . (0). . Kam D. Dahlquist (talk | contribs) (Modified t test for each timepoint: fix formula)

     

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(cur | prev) . . (+52). . Kam D. Dahlquist (talk | contribs) (Sanity Check: Number of genes significantly changed: add label to link)

     

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(cur | prev) . . (-360). . Kam D. Dahlquist (talk | contribs) (replace opi1 with hmo1)

     

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(cur | prev) . . (+18). . Kam D. Dahlquist (talk | contribs) (replace wt with dHMO1)

     

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(cur | prev) . . (-22). . Kam D. Dahlquist (talk | contribs) (Looking at the raw data: fix links to SGD)

     

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(cur | prev) . . (+27). . Kam D. Dahlquist (talk | contribs) (Background: steps 1-3 done for you)

     

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(cur | prev) . . (+74). . Kam D. Dahlquist (talk | contribs) (Background: add link for YEASTRACT)

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