Difference between revisions of "HeartDiagnostic"
(New page: == Motivation: Case Scenario correlating increased Troponin measurements with Acute Coronary Syndrome == “Case Presentation: J.P. is an obese 55-year-old male with a history of gastroes...)
Revision as of 21:31, 2 December 2013
Motivation: Case Scenario correlating increased Troponin measurements with Acute Coronary Syndrome
“Case Presentation: J.P. is an obese 55-year-old male with a history of gastroesophageal reflux disease who presents to the emergency department with substernal chest pain that he attributes to a “large meal.” J.P. is pale and diaphoretic. An ECG shows tachycardia with normal sinus rhythm. J.P.’s troponin levels (decision limit >0.04 μg/L) at presentation and at 6 and 12 hours after presentation are 0.09, 4.41, and 19.62 μg/L, respectively.” http://www.circ.ahajournals.org/content/116/18/e501.full
“J.P.’s presentation and troponin results are consistent with the diagnosis of ACS (Figure 1A). An additional cTnI measurement, 48 hours after admission, revealed a downward trend in his troponin level. Because of the improved sensitivity and precision at low cTnI concentrations, the initial cTnI result indicated myocardial injury and the subsequent diagnosis of ACS.”