Haynes Lab:Notebook/Synthetic Biology and Bioinformatics for Predictable Control of Therapeutic Genes

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Phase 1/2: Bioinformatics

  • ChIP is available through the Encyclopedia of DNA Elements (ENCODE) and GALAXY serves as a tool for biomedical analysis. Using the two tools I extracted a list of genes with H3K27me3 near the transcription start site (promoter) from cancer cells lines (neuroblastoma, liver carcinoma, and erythroleukemia). I then went on to perform GO (Gene Ontology) Term analysis to formulate predictions on how PcTF may affect cell phenotype and growth.

Notes

  • Phase 1 is complete


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