Difference between revisions of "Haynes Lab:Notebook/Synthetic Biology and Bioinformatics for Predictable Control of Therapeutic Genes"

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(Notes)
(Notes)
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==Notes==
 
==Notes==
* Phase 1 in progress
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* Phase 1 is complete
  
  

Revision as of 18:56, 16 April 2013

<!-- sibboleth --><div id="lncal1" style="border:0px;"><div style="display:none;" id="id">lncal1</div><div style="display:none;" id="dtext">01/18/2012,01/25/2012,01/29/2012,02/07/2012,02/08/2012,02/10/2012,02/22/2012,02/27/2012,02/29/2012,03/04/2012,03/09/2012,03/10/2012,03/23/2012,03/24/2012,05/28/2012,05/29/2012,05/30/2012,06/06/2012,06/17/2012,06/18/2012,06/29/2012,07/23/2012</div><div style="display:none;" id="page">Haynes Lab:Notebook/Synthetic Biology and Bioinformatics for Predictable Control of Therapeutic Genes</div><div style="display:none;" id="fmt">yyyy/MM/dd</div><div style="display:none;" id="css">OWWNB</div><div style="display:none;" id="month"></div><div style="display:none;" id="year"></div><div style="display:none;" id="readonly">Y</div></div>

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Project Description/Abstract

  • Since a comprehensive ChIP map is not available for osteosarcoma, I will identify genes associated with H3K27me3 in liver (HepG2) and fibroblast (BJ) cell lines. ChIP is available through the Encyclopedia of DNA Elements (ENCODE) (3). I will extract a list of genes with H3K27me3 near the transcription start site (promoter) as well as genes with a broad distribution of H3K27me3 to determine later on if H3K27me3 localization influences Pc-TF function. I will also determine which CBX isoforms are at each locus to determine variations between H3K27me3 sites.

Notes

  • Phase 1 is complete


Recent changes

25 September 2017

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