Difference between revisions of "Haynes Lab:Notebook/Engineering PC-TFs"

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|colspan="2" style="background-color: #F2F2F2;" align="right"|[[{{FULLPAGENAME}}/Entry_Base|Customize your entry pages]] [[Help:Notebook/Project_Base/Customize_entry_page|<html><img src="/images/a/aa/Help.png" border="0" /></html>]]
 
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==Project Description/Abstract==
 
==Project Description/Abstract==
* Place short description of project or notes regarding this project
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[[Image:engineering_pctfs.jpg|300px|thumb|right|]]
 
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* Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically.
* Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Donec porta commodo tellus. Nam a est eget libero mollis tincidunt. Aliquam purus. Quisque nulla ligula, facilisis in, pulvinar sed, molestie a, quam. Vestibulum at pede. In in sem eget odio eleifend placerat. Phasellus ultricies felis quis sapien. Etiam molestie volutpat quam. Praesent pulvinar scelerisque mi. Nam mi urna, fringilla eu, mattis sed, venenatis id, nunc. Maecenas velit eros, congue ut, placerat in, ornare vel, sem. Aenean porta enim sit amet felis gravida posuere. Phasellus faucibus nibh et orci.
 
  
 
==Notes==
 
==Notes==
* Brady Laughlin's Spring 2012 project at the Haynes Lab at Arizona State University
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* Brady Laughlin's Spring/Fall 2012 project in the Haynes Lab at Arizona State University
 
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* BME 394 Honors Research Spring 2012 and Fall 2012
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*Brady was accepted into the Fulton Undergraduate Research Initiative (FURI) for the Spring 2013 and Fall 2013 semesters.
  
  

Revision as of 06:58, 3 September 2013

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Project Description/Abstract

Engineering pctfs.jpg
  • Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically.

Notes

  • Brady Laughlin's Spring/Fall 2012 project in the Haynes Lab at Arizona State University
  • BME 394 Honors Research Spring 2012 and Fall 2012
  • Brady was accepted into the Fulton Undergraduate Research Initiative (FURI) for the Spring 2013 and Fall 2013 semesters.


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