Difference between revisions of "Haynes Lab:Notebook/Engineering PC-TFs"

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==Project Description/Abstract==
 
==Project Description/Abstract==
 +
[[Image:engineering_pctfs.jpg|300px|thumb|right|]]
 
* Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically.
 
* Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically.
  
 
==Notes==
 
==Notes==
* Brady Laughlin's Spring 2012 project in the Haynes Lab at Arizona State University
+
* Brady Laughlin's Spring/Fall 2012 project in the Haynes Lab at Arizona State University
 
+
* BME 394 Honors Research Spring 2012 and Fall 2012
 +
*Brady was accepted into the Fulton Undergraduate Research Initiative (FURI) for the Spring 2013 and Fall 2013 semesters.
  
  

Revision as of 17:49, 28 July 2013

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Project Description/Abstract

Engineering pctfs.jpg
  • Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically.

Notes

  • Brady Laughlin's Spring/Fall 2012 project in the Haynes Lab at Arizona State University
  • BME 394 Honors Research Spring 2012 and Fall 2012
  • Brady was accepted into the Fulton Undergraduate Research Initiative (FURI) for the Spring 2013 and Fall 2013 semesters.


Recent changes

18 October 2017

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