Harvard:Biophysics 101/2007/04/10

What we have now

Sequence
RS#
OMIM
Parsed OMIM output
- Pubmed - reviews and related articles
- News (sort good from bad)
- Wikipedia

I added the names of those who signed up in class -Cchi 19:00, 11 April 2007 (EDT)

Please sign up for problems below

Prioritize RS# - How to quantify the criteria below?
- Disease relevance
  - Number of PMID's
  - Number of drugs for particular disease
  - Disease lists from WHO - cross ref with pubmed
  - CDC
  - Keywords in disease classification
    - Mesh terms - Deniz
    - Keywords from OMIM - Resmi
  - California excel table - frequency of diagnosis - Zach
  - Clustering algorithm (on the side) - Kay
- Frequency of deleterious allele
  - GeneCards
  - Clustering alleles with respect to genes and particular diseases
- Treatment
  - Emedicine - Tiff
  - Known drugs, devices, patents, total dolars spent
  - WHO - Hetmann and Cynthia
    - Curable
    - Treatable
    - Preventable
- Known alleles
- Penetrance
  - WIKI brainstorm - HapMap?? OMIM?
Web interface
- Not just script also paste in sequence - Xiaodi
- Maybe useful source for getting sequence data
Non OMIM based analysis of sequences - Chris
- SNPdb?
Presentation of Information
- Review articles
  - use PMID's for related review articles - Resmi
  - Beyond PubMed: Google scholar
- News
  - Beyond Google News, restricting to certain sites
- Social Network?