Difference between revisions of "Harvard:Biophysics 101/2007/04/10"

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**News (sort good from bad)
 
**News (sort good from bad)
 
**Wikipedia
 
**Wikipedia
 +
 +
==What we need==
 
<pre>
 
<pre>
 
Please sign up for problems below
 
Please sign up for problems below
 
</pre>
 
</pre>
 
==What we need==
 
  
 
*Prioritize RS# - How to quantify the criteria below?
 
*Prioritize RS# - How to quantify the criteria below?

Revision as of 08:15, 10 April 2007

What we have now

  • Sequence
  • RS#
  • OMIM
  • Parsed OMIM output
    • Pubmed - reviews and related articles
    • News (sort good from bad)
    • Wikipedia

What we need

Please sign up for problems below
  • Prioritize RS# - How to quantify the criteria below?
    • Disease relevance
      • Number of PMID's
      • Number of drugs for particular disease
      • Disease lists from WHO - cross ref with pubmed
    • Frequency of deleterious allele
    • Clustering alleles for relevance to particular diseases
    • Treatment
    • Known alleles
    • Penetrance
  • Web interface
    • Not just script also paste in sequence
    • Maybe useful source for getting sequence data
  • Non OMIM based analysis of sequences