Harvard:Biophysics 101/2007/04/10: Difference between revisions

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**News (sort good from bad)
**News (sort good from bad)
**Wikipedia
**Wikipedia
==What we need==
<pre>
<pre>
Please sign up for problems below
Please sign up for problems below
</pre>
</pre>
==What we need==


*Prioritize RS# - How to quantify the criteria below?
*Prioritize RS# - How to quantify the criteria below?

Revision as of 08:15, 10 April 2007

What we have now

  • Sequence
  • RS#
  • OMIM
  • Parsed OMIM output
    • Pubmed - reviews and related articles
    • News (sort good from bad)
    • Wikipedia

What we need

Please sign up for problems below
  • Prioritize RS# - How to quantify the criteria below?
    • Disease relevance
      • Number of PMID's
      • Number of drugs for particular disease
      • Disease lists from WHO - cross ref with pubmed
    • Frequency of deleterious allele
    • Clustering alleles for relevance to particular diseases
    • Treatment
    • Known alleles
    • Penetrance
  • Web interface
    • Not just script also paste in sequence
    • Maybe useful source for getting sequence data
  • Non OMIM based analysis of sequences
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