Hartman Behavioral Neuroscience Lab

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Our lab at Loma Linda University in southern California primarily uses animal models to understand the biological basis of learning/memory and how aging, brain injury or disease can alter behavior. Techniques used include behavioral assessment (e.g., water maze) of rats and genetically modified (transgenic / knockout) mice, pharmacology (e.g., manipulation of behavior with various drugs), small animal surgery (e.g., intracardial perfusion, electrolytic brain lesions, induction of ischemic stroke), histology / immunohistochemistry (e.g., visualization of amyloid plaques in brain slices), stereological microscopy (unbiased quantification of brain structures under a microscope), and biochemistry (e.g., protein assays of brain tissue using Western blot and ELISA).