Difference between revisions of "Hartman Behavioral Neuroscience Lab"

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Our [http://en.wikipedia.org/wiki/Neuroscience#Major_branches behavioral neuroscience] lab at [[Loma Linda University]] in [http://maps.google.com/maps?f=q&hl=en&geocode=&q=loma+linda,+ca&ie=UTF8&t=h&ll=35.245619,-117.246094&spn=8.268015,17.86377&z=6&iwloc=addr southern California] primarily uses animal models of neurological disease to understand their mechanisms and potential therapeutic treatments. Techniques used include behavioral assessment (e.g., [[Hartman Behavioral Neuroscience Lab:Protocols |water maze]]) of rats and genetically modified ([http://en.wikipedia.org/wiki/Transgenic transgenic] / [http://en.wikipedia.org/wiki/Knockout_%28genetics%29 knockout]) mice, pharmacology (e.g., manipulation of behavior with various drugs), small animal surgery (e.g., intracardial perfusion, electrolytic brain lesions, induction of ischemic stroke), [http://en.wikipedia.org/wiki/Histology histology] / [http://en.wikipedia.org/wiki/Immunohistochemistry immunohistochemistry] (e.g., visualization of amyloid plaques in brain slices), [http://en.wikipedia.org/wiki/Stereology stereological] microscopy (unbiased quantification of brain structures under a microscope), and [http://en.wikipedia.org/wiki/Biochemistry biochemistry] (e.g., protein assays of brain tissue using [http://en.wikipedia.org/wiki/Western_blot Western blot] and [http://en.wikipedia.org/wiki/ELISA ELISA]).
 
 
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[[Hartman Behavioral Neuroscience Lab| <font face="trebuchet ms" style="color:#ffffff"> '''Home''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 
[[Hartman Behavioral Neuroscience Lab:Members | <font face="trebuchet ms" style="color:#ffffff"> '''Lab Members''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 
[[Hartman Behavioral Neuroscience Lab:Research | <font face="trebuchet ms" style="color:#ffffff"> '''Research''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 
[[Hartman Behavioral Neuroscience Lab:Publications | <font face="trebuchet ms" style="color:#ffffff"> '''Publications''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 
[[Hartman Behavioral Neuroscience Lab:Notebook | <font face="trebuchet ms" style="color:#ffffff"> '''Lab notebook''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 
[[Hartman Behavioral Neuroscience Lab:Equipment | <font face="trebuchet ms" style="color:#ffffff"> '''Equipment''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 
[[Hartman Behavioral Neuroscience Lab:Back Door | <font face="trebuchet ms" style="color:#ffffff"> '''Internal''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 
 
 
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Latest revision as of 15:08, 29 April 2009

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Calendar        Pubs        Protocols        Tests used       

Our behavioral neuroscience lab at Loma Linda University in southern California primarily uses animal models of neurological disease to understand their mechanisms and potential therapeutic treatments. Techniques used include behavioral assessment (e.g., water maze) of rats and genetically modified (transgenic / knockout) mice, pharmacology (e.g., manipulation of behavior with various drugs), small animal surgery (e.g., intracardial perfusion, electrolytic brain lesions, induction of ischemic stroke), histology / immunohistochemistry (e.g., visualization of amyloid plaques in brain slices), stereological microscopy (unbiased quantification of brain structures under a microscope), and biochemistry (e.g., protein assays of brain tissue using Western blot and ELISA).