Difference between revisions of "Freimoser"

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[[Image:FloriansLab3.gif|center]]
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<h3>[[Freimoser:Group|Group]]</h3>
 
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*[[User:mstadler|Martha Stadler]]<BR>
 
* [[User:Huerlimann|Hans Caspar Hürlimann]]<BR>
 
* [[User:werner|Thomas Werner]]<BR>
 
* [[User:freimoser|Florian Freimoser]]<BR>
 
 
  
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[[Image:Florian1.jpg|left]]
 
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<h3>[[Freimoser:Research|Research]]</h3>
 
*Projects
 
*Poly P
 
<h3>[[Freimoser:Publications|Publications]]</h3>
 
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<h3>[[Freimoser:Protocols|Protocols]]</h3>
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<h2><b>Florian M. Freimoser, PhD</b></h2>
* [[Freimoser:Protocols:Yeast|Yeast]]
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<h3>Institute of Plant Sciences</h3>
*Poly P
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<b>Biochemistry and Physiology of Plants</b>
*DNA
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ETH Zurich, LFW D46.1<br>
*Protein
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Universit&auml;tsstr. 2<br>
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CH-8092 Zurich<br>
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Switzerland
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<br>
 
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Tel: +41 +44 632 38 44<br>
<h3>[[Freimoser:Recipes|Recipes]]</h3>
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Fax: +41 +44 632 10 44<br>
*Yeast media
 
*Other media
 
*Buffers (DNA)
 
*Buffers (Proteins)
 
  
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Please also visit our [http://www.polyphosphate.ethz.ch/ other web site!]
 
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<h3>[[Freimoser:Contact|Contact]]</h3>
 
 
 
ETH Zurich<BR>
 
Institute of Plant Sciences<BR>
 
Universitätsstr. 2<BR>
 
8092 Zürich<BR>
 
Switzerland<BR>
 
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<h3>The molecule we study is so plain<br>
 
<h3>The molecule we study is so plain<br>
 
the inorganic polyphosphate chain</h3>
 
the inorganic polyphosphate chain</h3>
 
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The focus of the research in
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Our group studies a simple
our group is a simple
 
 
molecule: <strong>inorganic
 
molecule: <strong>inorganic
 
polyphosphate (poly P)</strong>.<br>
 
polyphosphate (poly P)</strong>.<br>
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phosphate residues
 
phosphate residues
 
(from three to more than a thousand) that are
 
(from three to more than a thousand) that are
linked by energy-rich phosphoanhydride bonds. It has been detected
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linked by energy-rich phosphoanhydride bonds. It occurs ubiquitously in all living cells and regulates many molecular and biological processes. Nevertheless, poly P is scarcely studied and little is known about poly P metabolism and its exact molecular functions; especially in eukaryotes. In our group we have developed methods to quantify poly P, to stain and localize poly P and to screen for poly P binding proteins. We are using these tools to investigate poly P metabolism and functions in fungi, plants and algae. However, at the moment our main efforts are devoted to the study of poly P metabolism in the yeast ''Saccharomyces cerevisiae'' and of poly P in fungal cell walls.
in all organisms and living cells and was found in many organelles.
 
In eukaryotes, poly P is particularly
 
prominent in fungi, algae and trypanosomatids.
 
Poly P serves as a phosphate and energy store and regulates
 
enzymes, chromatin condensation
 
and translation. Poly P is also involved in bacterial pathogenicity,
 
survival during stationary phase in
 
bacteria and yeast, or the adaptation to alkaline and osmotic stress.
 
In the slime mold <i>Dictyostelium discoideum</i>, poly P regulates
 
development and predation behaviour, and in humans blood coagulation is
 
accelerated and fibrinolysis is delayed by poly P.
 
In our group we study poly P metabolism and functions in eukaryotes and
 
we work mostly with yeast, filamentous fungi and algae.
 
 
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Latest revision as of 12:55, 7 May 2008

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Florian1.jpg

Florian M. Freimoser, PhD

Institute of Plant Sciences

Biochemistry and Physiology of Plants ETH Zurich, LFW D46.1
Universitätsstr. 2
CH-8092 Zurich
Switzerland
Tel: +41 +44 632 38 44
Fax: +41 +44 632 10 44

Please also visit our other web site!

The molecule we study is so plain
the inorganic polyphosphate chain

Our group studies a simple molecule: inorganic polyphosphate (poly P).
Poly P is a linear polymer that consists of a variable number of phosphate residues (from three to more than a thousand) that are linked by energy-rich phosphoanhydride bonds. It occurs ubiquitously in all living cells and regulates many molecular and biological processes. Nevertheless, poly P is scarcely studied and little is known about poly P metabolism and its exact molecular functions; especially in eukaryotes. In our group we have developed methods to quantify poly P, to stain and localize poly P and to screen for poly P binding proteins. We are using these tools to investigate poly P metabolism and functions in fungi, plants and algae. However, at the moment our main efforts are devoted to the study of poly P metabolism in the yeast Saccharomyces cerevisiae and of poly P in fungal cell walls.

Polyphosphate.gif