Welcome to the Frankel Group
We are interested in the forces that hold together biological systems. For example the forces that hold together cancer cells in a tumor and the forces that bind drugs to a cell surface. The misfiring of these biological interactions can lead to,or be a result of disease. Thus the ultimate goal of our research is to inform the development of disease treatments based on knowledge of biological interactions. Work is highly interdisciplinary involving physics, engineering, biomedicine and chemistry.
Specifically we are looking at the following systems:
▪. Unfolding Disease One Molecule at a Time - Proteins involved in disease such as HIV, cancer and arthritis are potential therapeutic targets. Their unfolding and self assembly behaviour is examined at the single molecule level revealing insight into their function.
LATEST NEWS !!
Biorobot paper accepted!!
4 new papers in print related to protein unfolding
Welcome to the Lab to new PhD student Ana from Ecuador.
Cyberplasm receives media attention, here is the original press release living microrobot
Congratulations to Orr Yarkoni for passing his PhD viva for a thesis entitled "Engineering an inducible NO pathway to facilitate cell-electronics communication"
Congratulations to Darman Nordin for passing his PhD viva for a thesis entitled "Interaction of the extracellular matrix protein fibronectin with model cell membranes"