FCCT Biochemistry Lab:Reprints

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This is the list of recent publications of our group members with links to summaries or full texts.

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  • Novinec M., Lenarčič B., Baici T. (2012) Clusterin is a specific stabilizer and liberator of extracellular cathepsin K. FEBS Lett. 586(7), 1062-6. DOI
  • Novinec M., Pavšič M., Lenarčič B. (2012) A simple and efficient protocol for the production of recombinant cathepsin V and other cysteine cathepsins in soluble form in Escherichia coli. Protein Expr. Purif. 82(1), 1-5. DOI


  • Pavšič M., Lenarčič B. (2011) Expression, crystallization and preliminary X-ray characterization of the human epithelial cell-adhesion molecule ectodomain. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 67(11), 363-6. DOI
  • Škrlj N., Vranac T., Popović M., Čurin Šerbec V., Dolinar M. (2011) Specific binding of the pathogenic prion isoform: development and characterization of a humanized single-chain variable antibody fragment. PLOS One 6(1), e15783. DOI
  • Žerovnik E., Stoka V., Mirtič A., Gunčar G., Grdadolnik J., Staniforth R.A., Turk D., Turk V. (2011) Mechanisms of amyloid fibril formation - focus on domain-swapping. FEBS J. 278, 2263-2282. DOI


  • Nishimura A.L., Župunski V., Troakes C., Kathe C., Fratta P., Howe M., Gallo J.-M., Hortobágyi T., Shaw C.E., Rogelj B. (2010) Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration. Brain 133(6), 1763-1771. DOI
  • Novinec M., Kovačič L., Lenarčič B., Baici A. (2010) Conformational flexibility and allosteric regulation of cathepsin K. Biochem. J. 429 (2), 379-389. DOI.
  • Saul F.A., Prijatelj P., de Normand B.V., Villette B., Raynal B., Pungerčar J., Križaj I., Faure G. (2010) Comparative structural studies of two natural isoforms of Ammodytoxin, phospholipases A2 from Vipera ammodytes ammodytes which differ in neurotoxicity and anticoagulant activity. J. Struct. Biol. 169(3), 360-369. DOI.
  • Škrlj N., Vidrih Z., Dolinar M. (2010) A universal approach for promoter strength evaluation supported by the web-based tool PromCal. Anal. Biochem. 396, 83–90. DOI
  • Škrlj N., Čurin Šerbec V., Dolinar M. (2010) Single-chain Fv antibody fragments retain binding properties of the monoclonal antibody raised against peptide P1 of the human prion protein. Appl. Biochem. Biotechnol. 160, 1808-1821. DOI


  • Lovšin N., Peterlin B.M. (2009) APOBEC3 proteins inhibit LINE-1 retrotransposition in the absence of ORF1p binding. Ann. N. Y. Acad. Sci. 1178, 268-275. DOI
  • Low A., Okeoma C.M., Lovšin N., de Las Heras M., Taylor T.H., Peterlin B.M., Ross S.R., Fan H. (2009) Enhanced replication and pathogenesis of Moloney murine leukemia virus in mice defective in the murine APOBEC3 gene. Virology 385(2), 455-463. DOI
  • Pungerčar J.R., Caglić D., Sajid M., Dolinar M., Vasiljeva O., Požgan U., Turk D., Bogyo M., Turk V., Turk B. (2009) Autocatalytic processing of procathepsin B is triggered by proenzyme activity. FEBS J. 276(3), 660-668. DOI
  • Škrlj N., Erčulj N., Dolinar M. (2009) A versatile bacterial expression vector based on the synthetic biology plasmid pSB1. Prot. Expr. Purif. 64, 198-204 DOI


  • Yoshinaga K., Obata H., Jurukovski V., Mazzieri R., Chen Y., Zilberberg L., Huso D., Melamed J., Prijatelj P., Todorovic V., Dabovic B., Rifkin D.B. (2008) Perturbation of transforming growth factor (TGF)-beta1 association with latent TGF-beta binding protein yields inflammation and tumors. Proc. Natl. Acad. Sci. USA 105(48), 18758-18763. DOI
  • Halassy B., Habjanec L., Brgles M., Balija M.L., Leonardi A., Kovačič L., Prijatelj P., Tomasić J., Križaj I. (2008) The role of antibodies specific for toxic sPLA2s and haemorrhagins in neutralizing potential of antisera raised against Vipera ammodytes ammodytes venom. Compar. Biochem. Physiol. C: Toxicol. Pharmacol. 148 (2), 178-183. ScienceDirect
  • Prijatelj P., Jenko Pražnikar Z., Petan T., Križaj I., Pungerčar J. (2008) Mapping the structural determinants of presynaptic neurotoxicity of snake venom phospholipases A2. Toxicon 51(8) 1520-1529. ScienceDirect
  • Bubik A., Sedmak B., Novinec M., Lenarčič B., Lah T.T. (2008) Cytotoxic and peptidase inhibitory activities of selected non-hepatotoxic cyclic peptides from cyanobacteria. Biol. Chem. 389(10), 1339-1346. DOI
  • Novinec M., Kovačič L., Škrlj N., Turk V., Lenarčič B. (2008) Recombinant human SMOCs produced by in vitro refolding: calcium-binding properties and interactions with serum proteins. Prot. Expr. Purif. 62(1), 75-82. DOI
  • Aguiar R.S., Lovšin N., Tanuri A., Peterlin B.M. (2008) VPR.A3A chimera inhibits HIV replication. J. Biol. Chem. 283 (5), 2518-2525. JBC-online
  • Pavšič M., Turk V., Lenarčič B. (2008) Purification and characterization of a recombinant human testican-2 expressed in baculovirus-infected Sf9 insect cells. Prot. Expr. Purif. 58(1) 132-139. DOI
  • Lah J., Drobnak I., Dolinar M., Vesnaver G. (2008) What drives the binding of minor groove-directed ligands to DNA hairpins? Nucl. Acids Res. 36 (3), 897-904. Open Access


  • Ciglič M., Fekonja O., Kovač J., Oblak A., Pohar J., Skočaj M., Tkavc R., Benčina M., Panter G., Manček Keber M., Dolinar M., Jerala R. (2007) Engineered human cells: say no to sepsis. IET Synth. Biol. 1(1-2), 13-16. IET Digital Library
  • Novinec M., Grass R.N., Stark W.J., Turk V., Baici A., Lenarčič B. (2007) Interaction between human cathepsins K, L, and S and elastins. J. Biol. Chem. 282 (11), 7893-7902. PubMed
  • Okeoma C.M., Lovšin N., Peterlin B.M., Ross S.R. (2007) APOBEC3 inhibits mouse mammary tumour virus replication in vivo. Nature 445, 927-930. PubMed


  • Kosec G., Alvarez V., Agüero F., Sanchez D., Dolinar M., Turk B., Turk V., Cazzulo J.J. (2006) Metacaspases of Trypanosoma cruzi: possible candidates for programmed cell death mediators. Mol. Biochem. Parasitol. 145, 18-28. PubMed
  • Novinec M., Kordiš D., Turk V., Lenarčič B. (2006) Diversity and evolution of the thyroglobulin type-1 domain superfamily. Mol. Biol. Evol. 23(4),744-755. PubMed
  • Prijatelj P., Charnay M., Ivanovski G., Jenko Z., Pungercar J., Krizaj I., Faure G. (2006) The C-terminal and beta-wing regions of ammodytoxin A, a neurotoxic phospholipase A2 from Vipera ammodytes ammodytes, are critical for binding to factor Xa and for anticoagulant effect. Biochimie 88(1), 69-76. PubMed
  • Prijatelj P., Vardjan N., Rowan E.G., Križaj I., Pungerčar J. (2006) Binding to the high-affinity M-type receptor for secreted phospholipases A(2) is not obligatory for the presynaptic neurotoxicity of ammodytoxin A. Biochimie 88(10), 1425-1433. PubMed


  • Fontana L., Chen Y., Prijatelj P., Sakai T., Fassler R., Sakai L.Y., Rifkin D.B. (2005) Fibronectin is required for integrin alpha vbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1. FASEB J. 19(13), 1798-808. PubMed
  • Grujić M., Zavašnik-Bergant T., Pejler G., Renko M. (2005) Actinonin induces apoptosis in U937 leukemia cells. Cancer Lett. 223, 211-218. PubMed
  • Meh P., Pavšič M., Turk V., Baici A., Lenarčič B. (2005) Dual concentration-dependent activity of thyroglobulin type-1 domain of testican: specific inhibitor and substrate of cathepsin L. Biol. Chem. 386, 75-83. PubMed
  • Vasiljeva O., Dolinar M., Rozman Pungerčar J., Turk V., Turk B. (2005) Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans. FEBS Lett. 579, 1285-1290. PubMed
  • Zheng Y.H., Lovšin N., Peterlin B.M. (2005) Newly identified host factors modulate HIV replication. Immunol Lett. 97(2), 225-34. PubMed

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