Experimental design and data analysis: Difference between revisions
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* [http://scholar.google.de/ Google Scholar] - Google scientific material database and search machine | * [http://scholar.google.de/ Google Scholar] - Google scientific material database and search machine | ||
:"pro: citation count, con: order of articles not disclosed and oldest articles often on top" ~ j | :"pro: citation count, occasionally, direct access to PDFs, con: order of articles not disclosed and oldest articles often on top" ~ j | ||
* [[Image:Padlock-closed.png]] [http://www.currentprotocols.com/WileyCDA/ Current Protocols] - life science protocols, only paid access | * [[Image:Padlock-closed.png]] [http://www.currentprotocols.com/WileyCDA/ Current Protocols] - life science protocols, only paid access |
Revision as of 03:12, 3 April 2014
This page lists resources discussed in the Design and Analysis seminar and includes links to relevant further reading. Please feel free to add your own suggestions and comments to the sections. The course is run approximately yearly and takes places in the Institute of Biochemistry of the University of Tübingen. See the Institute's course page for dates and contact information.
Aim of the course
Experimental design and data analysis is a new graduate seminar piloted in 2013 to address the questions of how to plan an experiment and how to best analyze the resulting data. We look at how to do a proper background check, where to find the best protocols, how to formulate a useful hypothesis, methods to keep experiments on schedule, tools of data analysis, and finally we will talk about some psychological pitfalls frequently seen in the interpretation of results.
1. Selecting a project
- How to choose a good scientific problem. - 2009 review by Alon U in Mol. Cell
2. Planning your project
Background check, methods research
- PubMed - your classical literature database
- "weak in some areas of chemistry, physics, plant science, maths & stats" ~ j
- Google Scholar - Google scientific material database and search machine
- "pro: citation count, occasionally, direct access to PDFs, con: order of articles not disclosed and oldest articles often on top" ~ j
- Current Protocols - life science protocols, only paid access
- Cold Spring Harbor Protocols - protocols for subscribers, also publisher of the widespread Molecular Cloning book series
- JoVE - Journal of visualized experiments, some teasers available; see also OWW article on JoVE
Discussion forums
- Protocol Online and its subsection BioForum
- BioTechniques - techniques, tips, and questions concerning molecular and cell biology
- SEQanswers - deep sequencing discussion forum
Other
- 5 free project planning software suites - software review by Ingenium Llc., a web design company, from 2013
3. Data analysis
- overview diagram to decide which statistical test to use - in German by the University of Zürich
- Handbook of biological statistics - online textbook by John McDonald at U Delaware
- Dealing with outliers - very detailed essay on the topic
- video tutorial: non-parametric rank sum test with Excel - see how a basic rank sum test is done using Excel
- free Matlab alternative Octave
4. Psychological pitfalls
See also
- OpenWetWare Courses
- 2014 ILIAS course page (requires login)
- 2013 ILIAS course page (requires login)