Difference between revisions of "Error Detection & Correction in Replicating Machines"
|Line 14:||Line 14:|
Revision as of 19:25, 2 August 2005
Replication with Error Working Group
Biological systems are replicating machines that make (a small number of) errors during the machine replication process. From a practical engineering standpoint, we need to understand how to design biological systems that perform as expected. We can imagine that a future biological engineer might be called upon to design an 8-bit counter that has a p(working) > 0.99 upto 256 doubling events. Or, we can imagine needing to design a metabolic pathway that has a p(failure) > 0.99 after 3000 doubling events. And so on. In other words, the evolutionary stability, or lack thereof, for our engineering biological systems should become part of the initial system specification, and our designs should be able to meet these specifications. From a scientific perspective, we suspect that learning how to solve questions of error detection and correction in replicating machines will lead to a better understanding of biological evolution.
- PROPOSED 4-6p on Tuesday August 30 Room TBA
- PM on Tuesday July 26 suggested
- DE is OK
- TK, GJS, JG, JK, AL are pending
- Read/skim Hausler paper
- Read/skim Kelly thesis proposal
Suggested Folks (not yet contacted/signed up)
- Norm Margolus
- Jonathan Rees