Crisanti:Projects
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Transgenic mosquitos for vector control
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Homing endonuclease genes as a gene drive system in Anopheles gambiae
Together with a number of other research groups our lab has engaged in a long-term effort to assess the potential of homing endonuclease genes (HEGs) as new tools for mosquito population engineering and control (gates foundation grand challenge #7). To achive this aim we will measure the homing frequency of natural HEGs in the main human malaria vector Anopheles gambiae. The long term goal is to engineer homing endonucleases against essential mosquitos genes and test their capability to spread, which could be used to put a genetic load on the population or to drive a refractory gene through the population.
Protein Microarrays as a high-throughput Tool for Serodiagnosis of Disease
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