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Our lab is interested in transposons using an approach combining biochemistry, cell biology, bioinformatics and mathematical modelling. <br/>
Our lab is interested in transposons using an approach combining biochemistry, cell biology, bioinformatics and mathematical modelling. <br/>


The main focuses of the lab are on: <br/>
Our [[Chalmers:Research| current projects]] are: <br/>
- Determination of the mariner transposition mechanism <br/>
- To determine the mechanism of mariner transposition <br/>
- Molecular domestication of mariner transposons in the human genome <br/>
- To find the functions of a primate-specific domesticated transposase <br/>
- Development of mariner transposons as gene vectors <br/>
- To develop mariner transposons as gene vectors <br/>


See the [[Chalmers:Research| research]] page for more details.


'''Last paper:'''
'''
== Last paper: ==
'''
Claeys Bouuaert C, Chalmers R. [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0053690 Hsmar1 Transposition Is Sensitive to the Topology of the Transposon Donor and the Target.] PLoS ONE. 2013 Jan 14;8(1): e53690.
Claeys Bouuaert C, Chalmers R. [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0053690 Hsmar1 Transposition Is Sensitive to the Topology of the Transposon Donor and the Target.] PLoS ONE. 2013 Jan 14;8(1): e53690.

Revision as of 11:32, 7 April 2013

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Our lab is interested in transposons using an approach combining biochemistry, cell biology, bioinformatics and mathematical modelling.

Our current projects are:
- To determine the mechanism of mariner transposition
- To find the functions of a primate-specific domesticated transposase
- To develop mariner transposons as gene vectors


Last paper:

Claeys Bouuaert C, Chalmers R. Hsmar1 Transposition Is Sensitive to the Topology of the Transposon Donor and the Target. PLoS ONE. 2013 Jan 14;8(1): e53690.