Difference between revisions of "Cell Transformation Group:Ongoing Research"

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Another part of our lab investigates the function of telomere length and telomere maintenance mechanisms in the growth and proliferation of brain cancers, specifically [http://en.wikipedia.org/wiki/Glioblastoma_multiforme Glioblastoma multiforme].
 
Another part of our lab investigates the function of telomere length and telomere maintenance mechanisms in the growth and proliferation of brain cancers, specifically [http://en.wikipedia.org/wiki/Glioblastoma_multiforme Glioblastoma multiforme].
  
==''p53<sup>-/-</sup> mice''==
+
==''p53 mutant mice''==
  
 
We have two strains of [http://p53.bii.a-star.edu.sg/index.php p53] defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis.
 
We have two strains of [http://p53.bii.a-star.edu.sg/index.php p53] defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis.

Latest revision as of 14:43, 15 January 2009

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YBX-1

Our primary research focus is the investigation of YBX-1 structure, function and interactions in vitro and ex vivo as a cancer oncogene.

Telomeres

Another part of our lab investigates the function of telomere length and telomere maintenance mechanisms in the growth and proliferation of brain cancers, specifically Glioblastoma multiforme.

p53 mutant mice

We have two strains of p53 defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis.