CH391L/S13/Topics: Difference between revisions
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=== Ancestral Sequence Reconstruction | |||
http://fastml.tau.ac.il/ | |||
== Other == | == Other == |
Revision as of 18:25, 6 January 2013
This is a brainstorming page...
What is synthetic biology?
http://www.plosone.org/article/info:doi%2F10.1371%2Fjournal.pone.0034368
http://www.buzzfeed.com/atmccann/how-to-code-a-life
Videos
Imperial College iGEM team documentary (50 min) http://www.youtube.com/watch?v=ushmgPM7HT8
E. chromi http://vimeo.com/19759432
Recent/Upcoming Meetings
http://www.keystonesymposia.org/index.cfm?e=web.Meeting.Program&meetingid=1238
New Topics
Algal biofuels
http://joulefuels.com/how-it-works
DNA computation / nanomachines
- Langecker M, Arnaut V, Martin TG, List J, Renner S, Mayer M, Dietz H, and Simmel FC. Synthetic lipid membrane channels formed by designed DNA nanostructures. Science. 2012 Nov 16;338(6109):932-6. DOI:10.1126/science.1225624 |
DNA origami to design functional structures
Spider Goats
"Spider Goats" - synthetic silk production. Video - http://www.fieldtest.us/bio.shtml
Pathogen synthesis
- Cello J, Paul AV, and Wimmer E. Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template. Science. 2002 Aug 9;297(5583):1016-8. DOI:10.1126/science.1072266 |
Polio virus
- Herfst S, Schrauwen EJ, Linster M, Chutinimitkul S, de Wit E, Munster VJ, Sorrell EM, Bestebroer TM, Burke DF, Smith DJ, Rimmelzwaan GF, Osterhaus AD, and Fouchier RA. Airborne transmission of influenza A/H5N1 virus between ferrets. Science. 2012 Jun 22;336(6088):1534-41. DOI:10.1126/science.1213362 |
AIrborne H5N1
- Russell CA, Fonville JM, Brown AE, Burke DF, Smith DL, James SL, Herfst S, van Boheemen S, Linster M, Schrauwen EJ, Katzelnick L, Mosterín A, Kuiken T, Maher E, Neumann G, Osterhaus AD, Kawaoka Y, Fouchier RA, and Smith DJ. The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host. Science. 2012 Jun 22;336(6088):1541-7. DOI:10.1126/science.1222526 |
AIrborne H5N1
Airborne H5N1 publication debate http://www.nytimes.com/2011/12/27/science/debate-persists-on-deadly-flu-made-airborne.html?pagewanted=all&_r=0 http://www.sciencemag.org/content/336/6088/1521.full
Riboswitches / Aptamer Biosensors
- Davidson ME, Harbaugh SV, Chushak YG, Stone MO, and Kelley-Loughnane N. Development of a 2,4-dinitrotoluene-responsive synthetic riboswitch in E. coli cells. ACS Chem Biol. 2013 Jan 18;8(1):234-41. DOI:10.1021/cb300274g |
DNT/TNT riboswitch
- Ehrentreich-Förster E, Orgel D, Krause-Griep A, Cech B, Erdmann VA, Bier F, Scheller FW, and Rimmele M. Biosensor-based on-site explosives detection using aptamers as recognition elements. Anal Bioanal Chem. 2008 Jul;391(5):1793-800. DOI:10.1007/s00216-008-2150-5 |
TNT aptamer
- Stojanovic MN, de Prada P, and Landry DW. Aptamer-based folding fluorescent sensor for cocaine. J Am Chem Soc. 2001 May 30;123(21):4928-31. DOI:10.1021/ja0038171 |
Cocaine aptamer biosensor
- Stojanovic MN and Landry DW. Aptamer-based colorimetric probe for cocaine. J Am Chem Soc. 2002 Aug 21;124(33):9678-9. DOI:10.1021/ja0259483 |
Cocaine aptamer biosensor, next iteration
Gene Therapy
Topic Updates
Refactoring
- Temme K, Zhao D, and Voigt CA. Refactoring the nitrogen fixation gene cluster from Klebsiella oxytoca. Proc Natl Acad Sci U S A. 2012 May 1;109(18):7085-90. DOI:10.1073/pnas.1120788109 |
Refactoring Nitrogen fixation gene cluster
=== Ancestral Sequence Reconstruction
Other
Humor
https://www.facebook.com/IgemMemes
Software
Other synthetic biology courses
http://soslab.ee.washington.edu/synthbio/index.php/Main_Page