Difference between revisions of "CH391L/S13/Probiotics"

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Revision as of 16:12, 10 March 2013





List of


Directed evolution of a thermostable esterase

iGEM links

http://2012.igem.org/Team:Trieste/project/overview http://2009.igem.org/Team:Stanford/ProjectPage

Media links

http://www.npr.org/2011/09/02/140146780/probiotic-bacteria-chill-out-anxious-mice http://www.telegraph.co.uk/health/healthnews/8261808/Designer-probiotic-yogurts-could-help-people-lose-weight.html


  1. Romero PA and Arnold FH. Exploring protein fitness landscapes by directed evolution. Nat Rev Mol Cell Bio, 2009. [Romero2009]
  2. Crameri A, Whitehorn EA, Tate E, Stemmer WP. Improved green fluorescent protein by molecular evolution using DNA shuffling. Nat Biotechnol, 1996. [Stemmer1995]
  3. Giver L, Gershenson A, Freskgard PO, Arnold FH. Directed evolution of a thermostable esterase. Proc Natl Acad Sci USA, 1998. [Giver1998]
  4. Cadwell RC and Joyce GF. Randomization of genes by PCR mutagenesis. Genome Res, 1992. [Cadwell1992]
  5. Abou-Nader M and Benedik MJ. Rapid generation of random mutant libraries. Bioeng Bugs, 2010. [Abou-Nader2010]
  6. Stemmer WP. Rapid evolution of a protein by in vitro DNA shuffling. Nature, 1994. [Stemmer1994]
  7. Lin H and Cornish VW. Screening and selection methods for large-scale analysis of protein function. [Lin2002]
  8. Leemhuis H, Kelly RM, Dijkhuizen L. Directed evolution of enzymes: library screening strategies. IUBMB Life, 2009. [Leemhuis2009]