CH391L/S12/Artemisinic Acid Engineering
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Introduction
Types of Selectable Markers
Antibiotic
Herbicidal
Auxotrophic
Other
Types of Screening
Blue/White Screening
Green Fluorescent Protein Screening
Artificial Selection
Previous iGEM Examples
http://en.wikipedia.org/wiki/Artemisinin
References
- Ro DK, Paradise EM, Ouellet M, Fisher KJ, Newman KL, Ndungu JM, Ho KA, Eachus RA, Ham TS, Kirby J, Chang MC, Withers ST, Shiba Y, Sarpong R, and Keasling JD. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature. 2006 Apr 13;440(7086):940-3. DOI:10.1038/nature04640 |
- Chang MC, Eachus RA, Trieu W, Ro DK, and Keasling JD. Engineering Escherichia coli for production of functionalized terpenoids using plant P450s. Nat Chem Biol. 2007 May;3(5):274-7. DOI:10.1038/nchembio875 |
