Burkart:Publications

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Burkart Lab

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Publications

  1. Meier JL and Burkart MD. Chapter 9. Synthetic probes for polyketide and nonribosomal peptide biosynthetic enzymes. Methods Enzymol. 2009;458:219-54. DOI:10.1016/S0076-6879(09)04809-5 | PubMed ID:19374985 | HubMed [1]
  2. Hur GH, Meier JL, Baskin J, Codelli JA, Bertozzi CR, Marahiel MA, and Burkart MD. Crosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesis. Chem Biol. 2009 Apr 24;16(4):372-81. DOI:10.1016/j.chembiol.2009.02.009 | PubMed ID:19345117 | HubMed [2]
  3. Mercer AC, Meier JL, Torpey JW, and Burkart MD. In vivo modification of native carrier protein domains. Chembiochem. 2009 Apr 17;10(6):1091-100. DOI:10.1002/cbic.200800838 | PubMed ID:19308927 | HubMed [3]
  4. Mercer AC, Meier JL, Hur GH, Smith AR, and Burkart MD. Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5991-4. DOI:10.1016/j.bmcl.2008.07.078 | PubMed ID:18701278 | HubMed [4]
  5. Worthington AS, Hur GH, Meier JL, Cheng Q, Moore BS, and Burkart MD. Probing the compatibility of type II ketosynthase-carrier protein partners. Chembiochem. 2008 Sep 1;9(13):2096-103. DOI:10.1002/cbic.200800198 | PubMed ID:18666307 | HubMed [5]
  6. Meier JL, Barrows-Yano T, Foley TL, Wike CL, and Burkart MD. The unusual macrocycle forming thioesterase of mycolactone. Mol Biosyst. 2008 Jun;4(6):663-71. DOI:10.1039/b801397g | PubMed ID:18493665 | HubMed [6]
  7. Meier JL, Mercer AC, and Burkart MD. Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes. J Am Chem Soc. 2008 Apr 23;130(16):5443-5. DOI:10.1021/ja711263w | PubMed ID:18376827 | HubMed [7]
  8. Haushalter RW, Worthington AS, Hur GH, and Burkart MD. An orthogonal purification strategy for isolating crosslinked domains of modular synthases. Bioorg Med Chem Lett. 2008 May 15;18(10):3039-42. DOI:10.1016/j.bmcl.2008.01.026 | PubMed ID:18249538 | HubMed [8]
  9. Kapur S, Worthington A, Tang Y, Cane DE, Burkart MD, and Khosla C. Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase. Bioorg Med Chem Lett. 2008 May 15;18(10):3034-8. DOI:10.1016/j.bmcl.2008.01.073 | PubMed ID:18243693 | HubMed [9]
  10. Ko KS, Najmabadi P, La Clair JJ, and Burkart MD. Affinity analyses on moldable optical polycarbonate. Chembiochem. 2008 Jan 25;9(2):201-5. DOI:10.1002/cbic.200700468 | PubMed ID:18098256 | HubMed [10]
  11. Mandel AL, Jones BD, La Clair JJ, and Burkart MD. A synthetic entry to pladienolide B and FD-895. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5159-64. DOI:10.1016/j.bmcl.2007.06.094 | PubMed ID:17681759 | HubMed [11]
  12. Mercer AC and Burkart MD. The ubiquitous carrier protein--a window to metabolite biosynthesis. Nat Prod Rep. 2007 Aug;24(4):750-73. DOI:10.1039/b603921a | PubMed ID:17653358 | HubMed [12]
  13. Worthington AS and Burkart MD. The old is new again: asparagine oxidation in calcium-dependent antibiotic biosynthesis. ACS Chem Biol. 2007 Mar 20;2(3):152-4. DOI:10.1021/cb700053g | PubMed ID:17373761 | HubMed [13]
  14. Najmabadi P, La Clair JJ, and Burkart MD. A systems perspective to digital structures in molecular analysis. Org Biomol Chem. 2007 Jan 21;5(2):214-22. DOI:10.1039/b614507h | PubMed ID:17205161 | HubMed [14]
  15. Foley TL and Burkart MD. Site-specific protein modification: advances and applications. Curr Opin Chem Biol. 2007 Feb;11(1):12-9. DOI:10.1016/j.cbpa.2006.11.036 | PubMed ID:17189712 | HubMed [15]
  16. Worthington AS, Rivera H, Torpey JW, Alexander MD, and Burkart MD. Mechanism-based protein cross-linking probes to investigate carrier protein-mediated biosynthesis. ACS Chem Biol. 2006 Dec 20;1(11):687-91. DOI:10.1021/cb6003965 | PubMed ID:17184132 | HubMed [16]
  17. Alexander MD, Fontaine SD, La Clair JJ, Dipasquale AG, Rheingold AL, and Burkart MD. Synthesis of the mycolactone core by ring-closing metathesis. Chem Commun (Camb). 2006 Nov 28(44):4602-4. DOI:10.1039/b609408b | PubMed ID:17082856 | HubMed [17]
  18. Meier JL, Mercer AC, Rivera H Jr, and Burkart MD. Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification. J Am Chem Soc. 2006 Sep 20;128(37):12174-84. DOI:10.1021/ja063217n | PubMed ID:16967968 | HubMed [18]
  19. Alexander MD, Burkart MD, Leonard MS, Portonovo P, Liang B, Ding X, Joullié MM, Gulledge BM, Aggen JB, Chamberlin AR, Sandler J, Fenical W, Cui J, Gharpure SJ, Polosukhin A, Zhang HR, Evans PA, Richardson AD, Harper MK, Ireland CM, Vong BG, Brady TP, Theodorakis EA, and La Clair JJ. A central strategy for converting natural products into fluorescent probes. Chembiochem. 2006 Mar;7(3):409-16. DOI:10.1002/cbic.200500466 | PubMed ID:16432909 | HubMed [19]
  20. Mercer AC and Burkart MD. Chemical expansion of cofactor activity. Nat Chem Biol. 2006 Jan;2(1):8-10. DOI:10.1038/nchembio0106-8 | PubMed ID:16408081 | HubMed [20]
  21. Worthington AS and Burkart MD. One-pot chemo-enzymatic synthesis of reporter-modified proteins. Org Biomol Chem. 2006 Jan 7;4(1):44-6. DOI:10.1039/b512735a | PubMed ID:16357994 | HubMed [21]
  22. Shute TS, Matsushita M, Dickerson TJ, La Clair JJ, Janda KD, and Burkart MD. A site-specific bifunctional protein labeling system for affinity and fluorescent analysis. Bioconjug Chem. 2005 Nov-Dec;16(6):1352-5. DOI:10.1021/bc050213j | PubMed ID:16287229 | HubMed [22]
  23. Clarke KM, Mercer AC, La Clair JJ, and Burkart MD. In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues. J Am Chem Soc. 2005 Aug 17;127(32):11234-5. DOI:10.1021/ja052911k | PubMed ID:16089439 | HubMed [23]
  24. Mercer AC, La Clair JJ, and Burkart MD. Fluorescent multiplex analysis of carrier protein post-translational modification. Chembiochem. 2005 Aug;6(8):1335-7. DOI:10.1002/cbic.200500051 | PubMed ID:15997462 | HubMed [24]
  25. Clarke KM, La Clair JJ, and Burkart MD. A three-component photoreversible tag for thiols. J Org Chem. 2005 Apr 29;70(9):3709-11. DOI:10.1021/jo0481396 | PubMed ID:15845011 | HubMed [25]
  26. Mercer AC and Burkart MD. Enzyme-assisted antibiotic engineering--the Wright way. Chem Biol. 2005 Feb;12(2):147-8. DOI:10.1016/j.chembiol.2005.01.010 | PubMed ID:15734642 | HubMed [26]
  27. Mandel AL, La Clair JJ, and Burkart MD. Modular synthesis of pantetheine and phosphopantetheine. Org Lett. 2004 Dec 23;6(26):4801-3. DOI:10.1021/ol048853+ | PubMed ID:15606070 | HubMed [27]
  28. La Clair JJ, Foley TL, Schegg TR, Regan CM, and Burkart MD. Manipulation of carrier proteins in antibiotic biosynthesis. Chem Biol. 2004 Feb;11(2):195-201. DOI:10.1016/j.chembiol.2004.02.010 | PubMed ID:15123281 | HubMed [28]
  29. Burkart MD. Metabolic engineering--a genetic toolbox for small molecule organic synthesis. Org Biomol Chem. 2003 Jan 7;1(1):1-4. PubMed ID:12929378 | HubMed [29]
All Medline abstracts: PubMed | HubMed