Difference between revisions of "Biomod/2012/Tohoku/Team Sendai/test"

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<a href="http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project/test">project/test</a>
 
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Revision as of 00:38, 14 October 2012

<html xmlns="http://www.w3.org/1999/xhtml"> <head> <meta http-equiv="Content-Type" content="text/html;charset=utf-8" /> <title>Team Sendai Top</title> <style type="text/css">

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<a href="http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project/test">project/test</a> <!-- コンテナ --> <div id="Container">

<!-- ヘッダー --> <div id="Header"> <h1><!--Team Sendai--><img src="http://openwetware.org/images/1/1c/Headtitle2.png"></h1> <p>Tohoku University</p> </div>

<!—トップメニュー --> <ul id="Topmenu"> <li><a href=" http://openwetware.org/wiki/Biomod/2012/Tohoku/Team_Sendai">Top</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project">Project</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Simulation">Simulation</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Results_%26_Discussion">Experiment</a></li> <li><a href=" http://openwetware.org/wiki/BIOMOD/2012/Team_Sendai/Movie">Diary</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Member ">Team</a></li> </ul>

<!-- コンテンツ --> <div id="Content"> <div id="pop"> <h2>Abstract</h2> <img src="http://openwetware.org/images/4/46/Format_D-Heart.jpg" alt="D-Heart" width="550px"><br> <p>

&nbsp;All the creatures on Earth are made of cells. The exterior and the interior of the cell are compartmentalized by biomembranes. A nanodevice that is able to actively transport only the specific oligonucleotide through the biomembrane has a great potential to deliver siRNA into the cell or to extract mRNA expressed in the cell.<br> Here, we decided to create a novel device with such a function. <br> We have designed a cylindrical injector/extractor device made of DNA origami. Inside the cylinder, a cascade of single stranded DNAs is planted. Once the outer-most ssDNA binds to a target oligonucleotide, the target is passed to the inner-ones one by one because of the higher bonding energy assigned to the inner ones.<br> We also investigate how the cylinder penetrates the biomembrane by using liposome as a model membrane.<br> <br> <strong>Selector</strong>: Single stranded DNA. Once the outer-most ssDNA binds to a target, the target is passed to the inner-ones one by one.</br> <strong>Gate</strong>: Cylindrical structure connecting the inside and outside like gates. A cascade of the "Selector" is planted in this. We can use this as an injector or extractor.</br> <strong>Membrane</strong>: The exterior and the interior of the cell are compartmentalized by biomembranes. We use liposome as a model membrane.</br> </p> </div>

<div id="pop"> <h2>Movie</h2> <!-- <p>Coming soon</p> --> <br><br> <p style="text-align:center;"> <table style="width:550px;height:400px;background-color:#ddd;text-align:center;valign:middle;"> <tr> <td>Coming soon...</td> </tr> </table> </p> </div> </div>

<!—フッターメニュー --> <ul id="Menu2"> <li><a href=" http://openwetware.org/wiki/Biomod/2012/Tohoku/Team_Sendai">Top</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project">Project</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Simulation">Simulation</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Results_%26_Discussion">Experiment</a></li> <li><a href=" http://openwetware.org/wiki/BIOMOD/2012/Team_Sendai/Movie">Diary</a></li> <li><a href="http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Member ">Team</a></li> </ul>

<!-- フッター --> <div id="Footer"> <address>Copyright (C) Team Sendai, All rights reserved.</address> </div>

<a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Top

">Legacy--Team Sendai B HP</a> </div>

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