Biomod/2012/Titech/Nano-Jugglers

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} </style> </head> <BODY> <div id="biomodlink"> <<a href="http://openwetware.org/wiki/Biomod">BIOMOD</a>|<a href="http://openwetware.org/wiki/Biomod/2012">2012</a>|Titech Nano-Jugglers </div> <div id="header"> <div id="navigation"> <div id="menu"> <ul> <li><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers"><br>Home<br><br></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Team/Students"><br>Team<br><br></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Project"><br>Project<br><br></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Results">Results<br>&<br>Methods</a></font></li> <li class="ach"><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Achievements"><br>Achievements<br><br></a> <li class="sup"><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Protocols"><br>Suppl. Info.<br><br></a></li> <li class="none"><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Acknowledgement"><br>Acknowledgements<br><br></a></li> </ul> </div> </div> </div> </BODY> </html>


Titech Nano-Jugglers developed Biomolecular Rocket, achieving three useful functions.

What's Biomolecular Rocket?

<html><body><img src="http://openwetware.org/images/a/a7/Homekaitei.jpg" border=0 width=440 height=330></a></body></html>       <html><iframe width="440" height="330" src="http://www.youtube.com/embed/TTjmoc0cSOI" frameborder="0" allowfullscreen></iframe></html>
Following the policy of the creators, we arranged and used the original score for the backgroud music of our YouTube video. We promise to observethe copyright compliance.
    We propose an extremely high-speed, controllable and rail-free molecular vehicle, "Biomolecular Rocket." The Biomolecular Rocket moves faster than a natural high-speed molecular motor, kinesin, by taking advantage of catalytic O2 production that progresses anywhere in a dilute H2O2 solution. For increasing the emission of O2 bubbles from the Biomolecular Rocket, we conjugated numerous catalytic engines to a micrometer-sized rocket body with the use of DNA. In addition, direction of the rail-free movement of the Biomolecular Rocket can be controlled, since we designed a photoresponsive DNA for allowing detachment of the engines from the body upon the UV light irradiation in a region-specific manner.
    The present study embodies the concept to utilize and control non-biological reactions by designing biomolecules for achieving novel functions implemented by synthetic molecular systems. We believe that our Biomolecular Rocket is a step toward advanced molecular robots that can move on long and rugged fields such as the inside of human body.