Biomod/2012/Titech/Nano-Jugglers

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} </style> </head> <BODY> <div id="biomodlink"> <<a href="http://openwetware.org/wiki/Biomod">BIOMOD</a>|<a href="http://openwetware.org/wiki/Biomod/2012">2012</a>|Titech Nano-Jugglers </div> <div id="header"> <div id="navigation"> <div id="menu"> <ul> <li><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers"><br>Home<br><br></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Team/Students"><br>Team<br><br></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Project"><br>Project<br><br></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Results">Results<br>&<br>Methods</a></font></li> <li class="ach"><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Achievements"><br>Achievements<br><br></a> <li class="sup"><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Protocols"><br>Suppl. Info.<br><br></a></li> <li class="none"><a href="http://openwetware.org/wiki/Biomod/2012/Titech/Nano-Jugglers/Acknowledgement"><br>Acknowledgements<br><br></a></li> </ul> </div> </div> </div> </BODY> </html>


Titech Nano-Jugglers developed Biomolecular Rocket, achieving three useful functions.

What's Biomolecular Rocket?

<html><body><td align="center"><img src="http://openwetware.org/images/8/88/HOME.jpg" border=0 width=440 height=330></a></td></body></html>       <html><iframe width="440" height="330" src="http://www.youtube.com/embed/tF2XyICuOSU" frameborder="0" allowfullscreen></iframe></html>
    We propose an extremely high-speed, controllable and rail-free molecular vehicle, "Biomolecular Rocket." The Biomolecular Rocket moves faster than a natural high-speed molecular motor, kinesin, by taking advantage of catalytic O2 production that progresses anywhere in a dilute H2O2 solution. For increasing the emission of O2 bubbles from the Biomolecular Rocket, we conjugated numerous catalytic engines to a micrometer-sized rocket body with the use of DNA. In addition, direction of the rail-free movement of the Biomolecular Rocket can be controlled, since we designed a photoresponsive DNA for allowing detachment of the engines from the body upon the UV light irradiation in a region-specific manner.
    The present study embodies the concept to utilize and control non-biological reactions by designing biomolecules for achieving novel functions implemented by synthetic molecular systems. We believe that our Biomolecular Rocket is a step toward advanced molecular robots that can move on long and rugged fields such as the inside of human body.