|
|
| (45 intermediate revisions by 3 users not shown) |
| Line 1: |
Line 1: |
| <div style="padding: 10px; width: 800px; border: 5px solid #333333;">
| | {{Template:Biomod/2011/Tianjin/TeamTianjin}} |
|
| |
|
| =Abstract= | | <div style="padding: 10px; width: 770px; border: 5px solid #333333;"> |
| Previous work has showcased the use of scaffolded DNA origami to self-assemble nanoscale, three-dimensional shapes with enclosed, hollow interiors. We explore the possibility of using such structures to load, entrap, and release soluble nanoscale cargo, with potential future applications in drug delivery and molecular signal amplification. Specifically, we design a rectangular box structure that can encapsulate gold nanoparticles and subsequently release them by a two-step process: a) photocleavage, which solubilizes the nanoparticle within the box, and b) introduction of a DNA signal, which opens the box by strand-displacement. We further investigate the use of an existing spherical origami design for similar purposes, and demonstrate opening of the sphere.
| | =Welcome to Tianjin Bio-Nano team wiki= |
| <br>
| | For watching our YouTube video, please see the '''video page'''. |
| =Video=
| |
| <html> | | <html> |
| <iframe width="560" height="315" src="http://www.youtube.com/embed/7gjLVt9onsw?rel=0" frameborder="0" allowfullscreen></iframe> | | <embed src="http://openwetware.org/images/c/c9/Biomod_tianjin_flash_2.swf" width=650px height=490px center></embed> |
| </html> | | </html> |
| <br>
| | |
| =Thank you= | | =Thank you= |
| [[Image:Biomod logo.png | 220px]]
| |
| [[Image:Wyss logo.gif | 220px]]
| |
| [[Image:Hhmi logo small.png| 220px]]
| |
|
| |
|
| </div> | | </div> |
|
| |
|
| <html>
| |
| <a href="http://www2.clustrmaps.com/counter/maps.php?url=http://openwetware.org/wiki/Biomod/2011/Tianjin" id="clustrMapsLink"><img src="http://www2.clustrmaps.com/counter/index2.php?url=http://openwetware.org/wiki/Biomod/2011/Tianjin" style="border:0px;" alt="Locations of visitors to this page" title="Locations of visitors to this page" id="clustrMapsImg" />
| |
| </html>
| |
|
| |
|
| __NOEDITSECTION__ | | __NOEDITSECTION__ |
| __NOTOC__ | | __NOTOC__ |
