Revision as of 13:21, 21 July 2007 by Reshma P. Shetty (New page: Some interesting facts <cite>Muller-Hill-1996</cite> *A tetramer of 4 identical subunits *Each subunit is 120kD. *Active only as a tetramer. *Mutations in some of the codons of the N-term...)
Some interesting facts 
- A tetramer of 4 identical subunits
- Each subunit is 120kD.
- Active only as a tetramer.
- Mutations in some of the codons of the N-terminal 60aa or C-terminal 100aa results in an inactive, dimeric β-galactosidase. 
- If the above sequences are deleted, the missing protein fragment can be replaced by the corresponding peptide. This is called intracistronic alpha or omega complementation respectively.
- Its N-terminal 23 residues can be replaced by any amino acid residues without affecting the enzymatic activity.