BMCB625:Nucl Code Intro

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Intro Slides (Histones & DNA Flexability)

Intro Power Point


  1. Satchwell SC, Drew HR, and Travers AA. Sequence periodicities in chicken nucleosome core DNA. J Mol Biol. 1986 Oct 20;191(4):659-75. PubMed ID:3806678 | HubMed [3]
  2. Widlund HR, Cao H, Simonsson S, Magnusson E, Simonsson T, Nielsen PE, Kahn JD, Crothers DM, and Kubista M. Identification and characterization of genomic nucleosome-positioning sequences. J Mol Biol. 1997 Apr 11;267(4):807-17. DOI:10.1006/jmbi.1997.0916 | PubMed ID:9135113 | HubMed [4]
  3. Schalch T, Duda S, Sargent DF, and Richmond TJ. X-ray structure of a tetranucleosome and its implications for the chromatin fibre. Nature. 2005 Jul 7;436(7047):138-41. DOI:10.1038/nature03686 | PubMed ID:16001076 | HubMed [5]
  4. Dorigo B, Schalch T, Kulangara A, Duda S, Schroeder RR, and Richmond TJ. Nucleosome arrays reveal the two-start organization of the chromatin fiber. Science. 2004 Nov 26;306(5701):1571-3. DOI:10.1126/science.1103124 | PubMed ID:15567867 | HubMed [6]
  5. Davey CA, Sargent DF, Luger K, Maeder AW, and Richmond TJ. Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution. J Mol Biol. 2002 Jun 21;319(5):1097-113. DOI:10.1016/S0022-2836(02)00386-8 | PubMed ID:12079350 | HubMed [7]
  6. Luger K, Rechsteiner TJ, and Richmond TJ. Expression and purification of recombinant histones and nucleosome reconstitution. Methods Mol Biol. 1999;119:1-16. DOI:10.1385/1-59259-681-9:1 | PubMed ID:10804500 | HubMed [8]
  7. El Hassan MA and Calladine CR. Two distinct modes of protein-induced bending in DNA. J Mol Biol. 1998 Sep 18;282(2):331-43. DOI:10.1006/jmbi.1998.1994 | PubMed ID:9735291 | HubMed [9]
  8. Travers AA. The structural basis of DNA flexibility. Philos Trans A Math Phys Eng Sci. 2004 Jul 15;362(1820):1423-38. DOI:10.1098/rsta.2004.1390 | PubMed ID:15306459 | HubMed [Must_Read]
  9. Ong MS, Richmond TJ, and Davey CA. DNA stretching and extreme kinking in the nucleosome core. J Mol Biol. 2007 May 11;368(4):1067-74. DOI:10.1016/j.jmb.2007.02.062 | PubMed ID:17379244 | HubMed [11]
  10. Richmond TJ and Davey CA. The structure of DNA in the nucleosome core. Nature. 2003 May 8;423(6936):145-50. DOI:10.1038/nature01595 | PubMed ID:12736678 | HubMed [Must_read]
All Medline abstracts: PubMed | HubMed

Chromatin: Structure and Function Alan Wolffe