Alexander Kanitz

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Revision as of 02:30, 5 March 2012 by Alexander Kanitz (talk | contribs) (Expertise)
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Contact Information

Alex.JPG
  • ETH Zurich

     Department of Chemistry and Applied Biosciences
     Institute of Pharmaceutical Sciences / Pharmacogenomics Unit
     Wolfgang Pauli-Strasse 10
     8093 Zurich
     Switzerland
     Google Maps link

Education

  • 12-2011: Molecular Life Sciences, Ph.D., ETH Zurich, Switzerland
  • 03-2007: Medical Biochemistry, M.Sc., University of Amsterdam, The Netherlands
  • 07-2004: Molecular Biotechnology, B.Sc., Technical University of Munich, Germany

Expertise

Profound knowledge of gene regulatory systems and networks with a particular focus on post-transcriptional gene regulation; strong background in biochemistry, molecular biology, cell biology; familiarity with bioinformatics and biotechnology concepts and methods

Current position

I am a grad student in the Gerber Lab at the ETH Zurich, working on post-transcriptional gene regulation, and was recruited through the Molecular Life Sciences program of the Life Science Zurich Graduate School.

Tentative title of the project: "Systematic Analysis of the Crosstalk between Regulatory RNA-Binding Proteins and the MicroRNA Machinery".

I am an initiator of the RNA Club Zurich and the (currently defunct) Zurich-based "Web Utilities and Software Seminar". Furthermore I maintain the web presence of the Gerber Lab (currently moving to the UK).

Previous labs

  • 2004-2005 - Seppen Lab, AMC Liver Center, University of Amsterdam, The Netherlands: "Lentiviral Gene Transfer of Chemically Inducible Hepatocyte Growth Factor Receptor and Liver Re-Targeting of Lentiviral Particles" / Supervisors: Dr. Jurgen Seppen, Prof. Ronald P.J. Oude-Elferink
  • 2004 - Skerra Lab, Institute of Biological Chemistry, Technical University of Munich, Germany: "Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes-bacteriophage A 500" / Supervisors: Dr. Ingo P. Korndörfer, Prof. Arne Skerra

Education

Publications

  1. Kanitz A and Gerber AP. Circuitry of mRNA regulation. Wiley Interdisciplinary Reviews: Systems Biology and Medicine 2009 Sep 30. doi: 10.1002/wsbm.55 [Paper4]
  2. Galgano A, Forrer M, Jaskiewicz L, Kanitz A, Zavolan M, and Gerber AP. Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system. PLoS One. 2008 Sep 8;3(9):e3164. DOI:10.1371/journal.pone.0003164 | PubMed ID:18776931 | HubMed [Paper3]
  3. Korndörfer IP, Kanitz A, Danzer J, Zimmer M, Loessner MJ, and Skerra A. Structural analysis of the L-alanoyl-D-glutamate endopeptidase domain of Listeria bacteriophage endolysin Ply500 reveals a new member of the LAS peptidase family. Acta Crystallogr D Biol Crystallogr. 2008 Jun;64(Pt 6):644-50. DOI:10.1107/S0907444908007890 | PubMed ID:18560152 | HubMed [Paper2]
  4. Markusic DM, Kanitz A, Oude-Elferink RP, and Seppen J. Preferential gene transfer of lentiviral vectors to liver-derived cells, using a hepatitis B peptide displayed on GP64. Hum Gene Ther. 2007 Jul;18(7):673-9. DOI:10.1089/hum.2007.027 | PubMed ID:17630838 | HubMed [Paper1]
All Medline abstracts: PubMed | HubMed

Useful links


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