Difference between revisions of "Alexander Kanitz"

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(Research Experience)
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==Education==
 
==Education==
*12-2011: '''Molecular Life Sciences''', Ph.D., ETH Zurich, Switzerland
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'''12-2011'''<br/>
*03-2007: '''Medical Biochemistry''', M.Sc., University of Amsterdam, The Netherlands
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'''Molecular Life Sciences''', Ph.D., ETH Zurich, Switzerland<br/><br/>
*07-2004: '''Molecular Biotechnology''', B.Sc., Technical University of Munich, Germany
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'''03-2007'''<br/>
 +
'''Medical Biochemistry''', M.Sc., University of Amsterdam, The Netherlands<br/><br/>
 +
'''07-2004'''<br/>
 +
'''Molecular Biotechnology''', B.Sc., Technical University of Munich, Germany
  
  

Revision as of 01:42, 5 March 2012

Contact Information

Alex.JPG
  • ETH Zurich

     Department of Chemistry and Applied Biosciences
     Institute of Pharmaceutical Sciences / Pharmacogenomics Unit
     Wolfgang Pauli-Strasse 10
     8093 Zurich
     Switzerland
     Google Maps link


Education

12-2011
Molecular Life Sciences, Ph.D., ETH Zurich, Switzerland

03-2007
Medical Biochemistry, M.Sc., University of Amsterdam, The Netherlands

07-2004
Molecular Biotechnology, B.Sc., Technical University of Munich, Germany


Expertise

Profound knowledge of gene regulatory systems and networks with a particular focus on post-transcriptional gene regulation; strong background in biochemistry, molecular biology, cell biology; familiarity with bioinformatics and biotechnology concepts and methods


Research Experience

11-2007 – 12-2011
Pharmacogenomics Unit, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland
Supervision: Prof. Dr. André Gerber, Prof. Dr. Michael Detmar
Project title: “Tools and strategies for the unraveling of post-transcriptional gene regulatory networks”

12-2006 – 02-2007
Swammerdam Institute of Life Sciences, University of Amsterdam, The Netherlands
Supervision: Prof. Dr. Stanley Brul, Dr. Hans van der Spek
Project title: “Status, complications and future prospects of highly active antiretroviral therapy”

02-2006 – 07-2006
Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore
Supervision: Prof. Dr. Vinay Tergaonkar
Project title: “Characterization of a putative IKK2 in Danio Rerio”

10-2004 – 09-2005
Department of Hepatology, Academic Medical Center, University of Amsterdam, The Netherlands
Supervision: Prof. Dr. Jurgen Seppen
Project titles: ”Lentiviral gene transfer of chemically inducible hepatocyte growth factor receptor” and “Liver re-targeting of lentiviral particles”

03-2004 – 07-2004
Institute of Biological Chemistry, Technical University of Munich, Germany
Supervision: Prof. Dr. Arne Skerra, Dr. habil. Ingo Korndörfer
Project title: ”Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes bacteriophage A 500”

08-2003 – 10-2003 & 07-2004 – 08-2004
Traineeships Research and Development at Micromet, Inc., Munich, Germany

Current position

I am a grad student in the Gerber Lab at the ETH Zurich, working on post-transcriptional gene regulation, and was recruited through the Molecular Life Sciences program of the Life Science Zurich Graduate School.

Tentative title of the project: "Systematic Analysis of the Crosstalk between Regulatory RNA-Binding Proteins and the MicroRNA Machinery".

I am an initiator of the RNA Club Zurich and the (currently defunct) Zurich-based "Web Utilities and Software Seminar". Furthermore I maintain the web presence of the Gerber Lab (currently moving to the UK).

Previous labs

  • 2004-2005 - Seppen Lab, AMC Liver Center, University of Amsterdam, The Netherlands: "Lentiviral Gene Transfer of Chemically Inducible Hepatocyte Growth Factor Receptor and Liver Re-Targeting of Lentiviral Particles" / Supervisors: Dr. Jurgen Seppen, Prof. Ronald P.J. Oude-Elferink
  • 2004 - Skerra Lab, Institute of Biological Chemistry, Technical University of Munich, Germany: "Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes-bacteriophage A 500" / Supervisors: Dr. Ingo P. Korndörfer, Prof. Arne Skerra

Education

Publications

  1. Kanitz A and Gerber AP. Circuitry of mRNA regulation. Wiley Interdisciplinary Reviews: Systems Biology and Medicine 2009 Sep 30. doi: 10.1002/wsbm.55 [Paper4]
  2. Galgano A, Forrer M, Jaskiewicz L, Kanitz A, Zavolan M, and Gerber AP. Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system. PLoS One. 2008 Sep 8;3(9):e3164. DOI:10.1371/journal.pone.0003164 | PubMed ID:18776931 | HubMed [Paper3]
  3. Korndörfer IP, Kanitz A, Danzer J, Zimmer M, Loessner MJ, and Skerra A. Structural analysis of the L-alanoyl-D-glutamate endopeptidase domain of Listeria bacteriophage endolysin Ply500 reveals a new member of the LAS peptidase family. Acta Crystallogr D Biol Crystallogr. 2008 Jun;64(Pt 6):644-50. DOI:10.1107/S0907444908007890 | PubMed ID:18560152 | HubMed [Paper2]
  4. Markusic DM, Kanitz A, Oude-Elferink RP, and Seppen J. Preferential gene transfer of lentiviral vectors to liver-derived cells, using a hepatitis B peptide displayed on GP64. Hum Gene Ther. 2007 Jul;18(7):673-9. DOI:10.1089/hum.2007.027 | PubMed ID:17630838 | HubMed [Paper1]
All Medline abstracts: PubMed | HubMed

Useful links


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