AhmadWeek5
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Saccharomyces Genome Database
- Which of these genes has a homolog (similar gene related by descent) in humans? What disease does a deficiency of this gene cause in humans?
- GDH2; the homologs are GLUD1 and GLUD2. "Deficiencies in the human homologs of glutamate dehydrogenase, GLUD1 and GLUD2, have been linked to hyperinsulinism-hyperammonemia syndrome and various neurological disorders." GDH2
- How is the expression of each of these genes regulated?
- GDH1- Expression is "regulated by nitrogen and carbon sources" GDH1
- GDH3- Expression is "regulated by nitrogen and carbon sources" GDH3
- GDH2- Expression is "sensitive to nitrogen catabolite repression and intracellular ammonia levels" GDH2
- GLN1- Expression is "regulated by nitrogen source and by amino acid limitation" GLN1
- GLT1- Expression is "regulated by nitrogen source" GLT1
- "L-glutamate". How many pathways does it participate in?
- It is in reactions as a reactant 26 times. It is in reactions as a product 29 times. L-glutamate
Kegg
Assignments
- Class Journal Week 1
- Journal Assignment Week 2
- Class Journal Week 2
- Journal Assignment Week 3
- Class Journal Week 3
- Journal Assignment Week 4
- Class Journal Week 4
- Journal Assignment Week 5
- Class Journal Week 5
- Journal Assignment Week 6
- Class Journal Week 6
- Journal Assignment Week 8
- Class Journal Week 8
- Journal Assignment Week 9
- Class Journal Week 9
- Journal Assignment Week 11
- Class Journal Week 11
- Journal Assignment Week 12
- Class Journal Week 12
- Journal Assignment Week 13
- Class Journal Week 13
- Assignment Week 13
- Journal Assignment Week 14
- Class Journal Week 14
- Assignment Week 14