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Saccharomyces Genome Database

  1. Which of these genes has a homolog (similar gene related by descent) in humans? What disease does a deficiency of this gene cause in humans?
    • GDH2; the homologs are GLUD1 and GLUD2. "Deficiencies in the human homologs of glutamate dehydrogenase, GLUD1 and GLUD2, have been linked to hyperinsulinism-hyperammonemia syndrome and various neurological disorders." GDH2
  2. How is the expression of each of these genes regulated?
    • GDH1- Expression is "regulated by nitrogen and carbon sources" GDH1
    • GDH3-