Difference between revisions of "AU Biomaterials Design Lab"

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{{Template:AU Biomaterials Design Lab}}
 
{{Template:AU Biomaterials Design Lab}}
The first semester of CHEM-570 will build off of the protein films research published by Bakshi, ''et al'' ([[doi:10.1021/jp110296y]]). We will be using expressed protein ligation (EPL) to make a fluorescent BSA fusion protein. The project in this notebook will detail the cloning and production of the EPL fluorescent BSA.<br>
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The American University Biomaterials Design Lab is a student run and operated laboratory course in the department of chemistry. Our goal is to develop methodology for the chemical modification of biocompatible materials and to tailor these new materials for medical and biotechnological applications. Our first semester of research will be the Fall of 2011. The efforts of this first semester will expand off of the work done developing protein films by Bakshi, ''et al'' ([[doi:10.1021/jp110296y]]). In this work, the authors synthesize a gold nanoparticle that is templated and solubilized by the protein bovine serum albumin (BSA). They then create a biocompatible film that encapsulates these gold nanoparticles. We will be developing techniques for chemically modifying the protein that encapsulates the gold nanoparticle and will test these methodologies on the nanoparticles while in solution and while in a film.<br>
 
<div style="text-align: center;">[[Image:AU BDLabs 1.png|450px]]</div><br>
 
<div style="text-align: center;">[[Image:AU BDLabs 1.png|450px]]</div><br>
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Latest revision as of 08:59, 19 July 2011

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The American University Biomaterials Design Lab is a student run and operated laboratory course in the department of chemistry. Our goal is to develop methodology for the chemical modification of biocompatible materials and to tailor these new materials for medical and biotechnological applications. Our first semester of research will be the Fall of 2011. The efforts of this first semester will expand off of the work done developing protein films by Bakshi, et al (doi:10.1021/jp110296y). In this work, the authors synthesize a gold nanoparticle that is templated and solubilized by the protein bovine serum albumin (BSA). They then create a biocompatible film that encapsulates these gold nanoparticles. We will be developing techniques for chemically modifying the protein that encapsulates the gold nanoparticle and will test these methodologies on the nanoparticles while in solution and while in a film.

AU BDLabs 1.png