User:Tkadm30/Notebook/Endocannabinoids/Synopsis: Difference between revisions
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(New page: == Synopsis == * Stimulation of endocannabinoid transport with polyunsaturated (22:6n-3) fatty acids (DHA, EPA) to target [https://en.wikipedia.org/wiki/Major_depressive_disorder major de...) |
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* Stimulation of endocannabinoid transport with polyunsaturated (22:6n-3) fatty acids (DHA, EPA) to target [https://en.wikipedia.org/wiki/Major_depressive_disorder major depressive disorders] (MDD) , epilepsy, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), posttraumatic stress disorder (PTSD), Parkinson's disease (PD), and Alzheimer's disease (AD). | * Stimulation of endocannabinoid transport with polyunsaturated (22:6n-3) fatty acids (DHA, EPA) to target [https://en.wikipedia.org/wiki/Major_depressive_disorder major depressive disorders] (MDD) , epilepsy, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), posttraumatic stress disorder (PTSD), Parkinson's disease (PD), and Alzheimer's disease (AD). | ||
* Distribution of endocannabinoid-dependent activity (LTP, synaptogenesis) in the hippocampus promoting brain-derived neurotrophic factor (BDNF) expression, a biological marker for learning-dependent synapse formation. [https://www.ncbi.nlm.nih.gov/pubmed/21035522 PMID] [https://www.ncbi.nlm.nih.gov/pubmed/24360280 PMID] | * Distribution of endocannabinoid-dependent protease activity (LTP, synaptogenesis) in the hippocampus promoting brain-derived neurotrophic factor (BDNF) expression, a biological marker for learning-dependent synapse formation. [https://www.ncbi.nlm.nih.gov/pubmed/21035522 PMID] [https://www.ncbi.nlm.nih.gov/pubmed/24360280 PMID] | ||
* Neuroprotective effects of the P2X7 receptor on excitatory (glutamatergic) synapses, [https://en.wikipedia.org/wiki/Synapsin synapsins], and in particular astrocytes are mediated by PPARs activation. [https://www.ncbi.nlm.nih.gov/pubmed/21376829 PMID] [https://www.ncbi.nlm.nih.gov/pubmed/14526074 PMID] | * Neuroprotective effects of the P2X7 receptor on excitatory (glutamatergic) synapses, [https://en.wikipedia.org/wiki/Synapsin synapsins], and in particular astrocytes are mediated by PPARs activation. [https://www.ncbi.nlm.nih.gov/pubmed/21376829 PMID] [https://www.ncbi.nlm.nih.gov/pubmed/14526074 PMID] | ||
** DHA supplementation improves mitochondrial function and neuronal survival. [https://www.ncbi.nlm.nih.gov/pubmed/22248591 PMID] | ** DHA supplementation improves mitochondrial function and neuronal survival. [https://www.ncbi.nlm.nih.gov/pubmed/22248591 PMID] |
Revision as of 13:42, 1 October 2015
Synopsis
- Stimulation of endocannabinoid transport with polyunsaturated (22:6n-3) fatty acids (DHA, EPA) to target major depressive disorders (MDD) , epilepsy, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), posttraumatic stress disorder (PTSD), Parkinson's disease (PD), and Alzheimer's disease (AD).
- Distribution of endocannabinoid-dependent protease activity (LTP, synaptogenesis) in the hippocampus promoting brain-derived neurotrophic factor (BDNF) expression, a biological marker for learning-dependent synapse formation. PMID PMID
- Neuroprotective effects of the P2X7 receptor on excitatory (glutamatergic) synapses, synapsins, and in particular astrocytes are mediated by PPARs activation. PMID PMID
- DHA supplementation improves mitochondrial function and neuronal survival. PMID
- Identification of a functional GPR40-GPR55 receptor heteromer with potent anti-inflammatory, antiglutamatergic and neuroprotective properties.
- Effects of the endothelial CB2 receptor persistent activation on monocyte subpopulations/microglial activation PMID