User:Xinming Tong

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Contact Info

  • Xinming Tong
  • Postdoctoral Fellow
  • Department of Orthopaedic Surgery, School of Medicine
  • Stanford University, CA, 94305
  • Email: xinming@stanford.edu[1]

I'm now working in the Fan Yang's Lab (Stem Cell and Biomaterials Engineering Laboratory) at Stanford University.

Experience

  • 2011 - , PostDoc, Department of Orthopaedic Surgery, School of Medicine, Stanford University
  • 2009 - 2011, PostDoc, Department of Chemical Engineering, Tsinghua University

Education

  • 2009, PhD in Material Science and Engineering, Beijing Institute of Technology
  • 2004, BE in Polymer Science and Engineering, Beijing Institute of Technology

Research interests

  • Biomimetic cell niche with well tunable properties for regulating cell behavior.

Publications

14. Tong, X.; Yang, F.*; Engineering Interpenetrating Network Hydrogels as Biomimetic Cell Niche with Independently Tunable Biochemical and Mechanical Properties, Biomaterials 2014, 35, 1807-15. [2]

13. Han, L.H.; Tong, X.; Yang, F.*; Photocrosslinkable PEG-based Microribbons for Forming 3D Macroporous Scaffolds with Decoupled Niche Properties, Advanced Materials 2013. [3]

12. Keeney, M.; Onyiah, S.; Zhang, Z.; Tong, X.; Han, L.H.; Yang, F., Modulating Polymer Chemistry to Enhance Non-viral Gene Delivery inside Hydrogels with Tunable Matrix Stiffness, Biomaterials 2013, 34, 9657-9665.[4]

11. Hammer, J. A.; Han, L. H.; Tong, X.; Yang, F.*; A Cell-friendly Process to Fabricate Hydrogels with Microchannel-like Porosity for Tissue Engineering. Tissue Eng. Part C, 2013, DOI: 10.1089/ten.TEC.2013.0176. [5]

10. Keeney, M.; Mathur, M.; Cheng, E.; Tong, X.; Yang, F.*; The Effects of Polymer End-group Chemistry and Order of Deposition on Controlled Protein Delivery from Layer-by-layer Assembly. Biomacromolecules, 2013, 14, 794-800. [6]

9. Tao,Y.; Tong, X.; Zhang, Y.; Lai, J., Huang, Y.; Jiang, Y.R.*; Guo, B.H.*, Evaluation of an in-situ chemically crosslinked hydrogel as a long-term vitreous substitute material, Acta Biomater., 2013, 9, 5022-5030. [7]

8. Tong, X.; Lai, J.; Guo, B.; Huang, Y.*, A new end group structure of PEG for hydrolysis- resistant biomaterials. J. Polym. Sci., Part A: Polym. Chem. 2011, 49, 1513-1516.[8]

7. Tong, X.; Guo, B.; Huang, Y., Toward the synthesis of sequence-controlled vinyl copolymers. Chem. Comm. 2011, 47, 1455-1457. [9]

6. Tong, X.; Gao, P.; Zhang, X.; Ye, L.; Zhang, A.; Feng, Z., End-capping double-chain stranded polypseudorotaxanes using lengthily tunable poly(2-hydroxyethyl methacrylate) blocks via atom transfer radical polymerization. Polym. Int. 2010, 59, 917-922.[10]

5. Tong, X.; Zhang, X.; Ye, L.; Zhang, A.; Feng, Z., Synthesis and characterization of block copolymers comprising a polyrotaxane middle block flanked by two brush-like PCL blocks. Soft Matter 2009, 5, 1848-1855.[11]

4. Tong, X.; Zhang, X.; Ye, L.; Zhang, A.; Feng, Z., Novel main-chain polyrotaxanes synthesized via ATRP of HEMA initiated with polypseudorotaxanes comprising BriB-PEG-iBBr and alpha-CDs. Polymer 2008, 49, 4489-4493. [12]

3. Tong, X.; Hou, D.; Zhang, X.; Ye, L.; Zhang, A.; Feng, Z.*, Synthesis and characterization of polyrotaxanes made from alpha-CDs threaded onto triblock copolymers with PEG as a central axle and flanked by two low molecular weight polystyrenes as outer stoppers. Chinese J. Poly. Sci. 2008, 26, 723-732.

2. Zhang, X.; Zhu, X.; Tong, X.; Ye, L.; Zhang, A.; Feng, Z.*, Novel main-chain polyrotaxanes synthesized via ATRP of HPMA in aqueous media. J. Polym. Sci., Part A: Polym. Chem. 2008, 46, 5283-5293.[13]

1. Hou, D.; Tong, X.; Yu, H.; Zhang, A.; Feng, Z.*, A kind of novel biodegradable hydrogel made from copolymerization of gelatin with polypseudorotaxanes based on alpha-CDs. Biomed. Mater. 2007, 2, S147-S152.[14]

Patents

4. Han, L.; Yang, F.; Tong, X. "Macroporous 3-D scaffolds for tissue engineering". (USPTO Provisional patent S12-089)
3. Yang, F.; Han, L.; Tong, X. "Dynamic macropore formation using multiple porogens". (USPTO Provisional patent S12-148)
2. Tao, Y.; Jiang, Y.; Guo, B.; Huang, Y.; Tong, X. "Application of in-situ crosslinking hydrogel capable of intraocular injection in preparing artificial vitreous bodies". (Chinese Patent CN 101934089, 2013.)
1. Tong, X.; Guo, B.; Lai, J.; Huang, Y., "Polymers that react with thiol groups and form hydrolysis-resistant linkages". ('Chinese Patent CN 101885841, 2012.)

Conference Presentations

4. Tong, X.; Yang, F. “Biomimetic Interpenetrating Network for Controlling Osteogenesis of Stem Cell in 3D Combinatorial Hydrogels”, 2013 Material Research Society Annual Spring Meeting, San Francisco, CA, 2013.
3. Tong, X.; Lee, S.; Bararpour, L.; Yang, F. “Long-Term Sustained Protein Release from Hydrogels by Tuning Poly(Ethylene Glycol) Structure and Degradation”, 2013 Material Research Society Annual Spring Meeting, San Francisco, CA, 2013.
2. Tong, X.; Yang, F. “Engineering Stem Cell Microenvironment with independently tunable biochemical and mechanical properties”, Oral presentation at 2012 Material Research Society Annual Spring Meeting, San Francisco, CA, 2012.
1. Tong, X.; Lai, J.; Guo, B.-H.; Huang, Y.; Tao, Y.; Jiang, Y.-R.; Zhang, Y.; Wang, X.-L., “PEG based hydrolysis-resistant in situ hydrogel for vitreous substitutes”, Poster presentation at 241st National Meeting and Exposition of the American Chemical Society, Anaheim, CA, 2011.

Awards

  • 2010, Young Scholar Grant from National Science Foundation of China (Grant No. 21004038).
    • Project: Synthesis of copolyrotaxane with controlled cyclodextrin sequence.
  • 2010, National Postdoctoral Fellowship (No. 20100470333).
    • Project: In situ forming sliding hydrogel.
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