User:Werdehausen

From OpenWetWare

Jump to: navigation, search

Contents

Contact information

Robert Werdehausen, M.D. - Resident in Anesthesiology

  • Departmental adress:

Department of Anesthesiology, University Hospital Düsseldorf
Building 12.42, Moorenstr. 5, 40225 Düsseldorf, Germany

  • Laboratory address (preferred mail adress):

Section of Experimental Anesthesiology, Heinrich-Heine-University of Düsseldorf
Building 23.02.01.R64, Universitätsstr. 1, 40225 Düsseldorf, Germany

  • Current position (Postdoctoral research fellowship):

Molecular Nociception Group (Head: Professor John N. Wood)
Institute for Biomedical Research (WIBR), University College London (UCL)
Gower Street, London WC1E 6BT, United Kingdom


Research interests

  • New techniques in regional anesthesia and pain medicine


  • Molecular mechanisms of pain perception


  • Effects of local and general anesthetics on chronic pain development


Selected publications

  • Expression of spinal cord microRNAs in a rat model of chronic neuropathic pain.
    Neuroscience Letters 2012 Jan 11;506(2):281-6. PMID: 22138088 Pubmed abstract


  • Lidocaine metabolites inhibit glycine transporter 1: a novel mechanism for the analgesic action of systemic lidocaine?
    Anesthesiology. 2012 Jan;116(1):147-58. PMID: 22133759 Pubmed abstract


  • Lipophilicity but not stereospecificity is a major determinant of local anaesthetic-induced cytotoxicity in human T-lymphoma cells.
    European Journal of Anaesthesiology 2012 Jan;29(1):35-41. PMID: 22012177 Pubmed abstract


  • The influence of adjuvants used in regional anesthesia on lidocaine-induced neurotoxicity in vitro.
    Regional Anesthesia and Pain Medicine 2011 Sep-Oct;36(5):436-43. PMID: 21857277 Pubmed abstract


  • The paravertebral lamina technique: a new regional anesthesia approach for breast surgery.
    Journal of Clinical Anesthesia 2011 Sep;23(6):443-50. PMID: 21752620 Pubmed abstract


  • Midazolam activates the intrinsic pathway of apoptosis independent of benzodiazepine and death receptor signaling.
    Regional Anesthesia and Pain Medicine 2011 Jul-Aug;36(4):343-9. PMID: 21701267 Pubmed abstract


  • Effect of continuous posttraumatic intrathecal nocistatin on the development of mechanical allodynia.
    Regional Anesthesia and Pain Medicine 2011 Jan-Feb;36(1):32-5. PMID: 21455086 Pubmed abstract


  • Benzethonium increases the cytotoxicity of S(+)-ketamine in lymphoma, neuronal, and glial cells.
    Anesthesia & Analgesia 2010 Dec;111(6):1389-93. PMID: 20889936 Pubmed abstract


  • Ketamine induces apoptosis via the mitochondrial pathway in human lymphocytes and neuronal cells.
    British Journal of Anaesthesia 2010 Sep;105(3):347-54. PMID: 20659914 Pubmed abstract


  • Apoptosis induction by different local anaesthetics in a neuroblastoma cell line.
    British Journal of Anaesthesia 2009 Nov;103(5):711-8. PMID: 19700777 Pubmed abstract


  • Loss of spinal glycinergic neurons is not necessary for development of neuropathic pain in transgenic mice expressing enhanced green fluorescent protein in glycinergic neurons.
    Neuroscience. 2009 Mar 31;159(3):1148-53. PMID: 19356695 Pubmed abstract


  • Lidocaine protects from myocardial damage due to ischemia and reperfusion in mice by its antiapoptotic effects.
    Anesthesiology. 2009 May;110(5):1041-9. PMID: 19352171 Pubmed abstract


  • Differential effects of spinally applied glycine transporter inhibitors on nociception in a rat model of neuropathic pain.
    Neuroscience Letters 2008 Nov 21;445(3):214-9. PMID: 18793697 Pubmed abstract


  • Skin temperature after interscalene brachial plexus blockade.
    Regional Anesthesia and Pain Medicine 2007 Nov-Dec;32(6):481-7. PMID: 18035293 Pubmed abstract


  • Stimulating catheter as a tool to evaluate peripheral nerve function during hip rotationplasty.
    Regional Anesthesia and Pain Medicine 2007 Nov-Dec;32(6):528-32. PMID: 18035301 Pubmed abstract


  • Lidocain induces apoptosis via the mitochondrial pathway independently of death receptor signaling.
    Anesthesiology. 2007 Jul;107(1):136-143. PMID: 17585225 Pubmed abstract


  • Does interscalene catheter placement with stimulating catheters improve postoperative pain or functional outcome after shoulder surgery?
    A prospective, randomized and double-blinded trial.

    Anesthesia & Analgesia 2007 Feb;104(2):442-7. PMID: 17242107 Pubmed abstract


  • Uniform distribution of skin-temperature increase after different regional-anesthesia techniques of the lower extremity.
    Regional Anesthesia and Pain Medicine 2007 Jan-Feb;32(1):73-8. PMID: 17196496 Pubmed abstract, PDF


  • Sedation during spinal anaesthesia in infants.
    British Journal of Anaesthesia 2006 Sep;97(3):380-4. PMID: 16816395 Pubmed abstract



Memberships

  • International Anesthesia Research Society (IARS)
  • German Society for Anesthesiology and Intensive Care Medicine (DGAI)
  • Subcommittee on Young Scientists (WAKWiN, DGAI)
  • Selected mentee of the Mentoring Program for Junior Investigators (DGAI)


Grants and awards

Personal tools