User:Sean D Colloms

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Sean D Colloms
Sean D Colloms

Education

  • 1991, PhD, University of Glasgow
  • 1987, BA, University of Cambridge


Research interests

  1. My lab at the University of Glasgow works on DNA transposition and site-specific recombination. These are DNA rearrangements that are catalysed by specific enzymes (transposases and site-specific recombinases) that recognise short DNA sequences, cleave the DNA backbone at these sequences, and then rejoin them in new configurations.
  • We are interested in the mechanism of site-specific recombination and transposition, and also their applications for Synthetic biology.
  • Together with William Brown (University of Nottingham), Oliver Ebenhoeh (University of Aberdeen / Heinrich Heine University Düsseldorf), Susan Rosser (University of Edinburgh), Maggie Smith (University of Nottingham), Marshall Stark (University of Glasgow), I have a BBSRC strategic longer and larger grant to develop large serine recombinases for Synthetic Biology and Biotechnology http://www.bbsrc.ac.uk/pa/grants/AwardDetails.aspx?FundingReference=BB/K003356/1.

We refer to this technology as SIDR for Serine Integrase Directional Recombination. The specific use of SIDR for gene assembly is referred to as Serine Integrase Recombinational Assembly SIRA

Publications

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  1. Error fetching PMID 24225316: [Paper]
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