User:Michael Benedik

Contact Info

Michael Benedik (an artistic interpretation)

• Michael Benedik
• Department of Biology
• Texas A&M University
• TAMU-3258
• College Station, TX 77843-3258
• email: benedik AT tamu.edu
• tel: 979-845-5776

Education

• 1982, PhD, Stanford University
• 1976, BS, University of Chicago

Research interests

1. Enzyme Engineering
2. Microbial Bioremediation
3. Microbial Genetics
4. Protein Secretion
5. Developing Tools for Biotechnology

Publications

1. Thuku RN, Brady D, Benedik MJ, and Sewell BT. Microbial nitrilases: versatile, spiral forming, industrial enzymes. J Appl Microbiol. 2009 Mar;106(3):703-27. DOI:10.1111/j.1365-2672.2008.03941.x |
2. Dent KC, Weber BW, Benedik MJ, and Sewell BT. The cyanide hydratase from Neurospora crassa forms a helix which has a dimeric repeat. Appl Microbiol Biotechnol. 2009 Feb;82(2):271-8. DOI:10.1007/s00253-008-1735-4 |
3. Basile LJ, Willson RC, Sewell BT, and Benedik MJ. Genome mining of cyanide-degrading nitrilases from filamentous fungi. Appl Microbiol Biotechnol. 2008 Sep;80(3):427-35. DOI:10.1007/s00253-008-1559-2 |
4. Woodward JD, Weber BW, Scheffer MP, Benedik MJ, Hoenger A, and Sewell BT. Helical structure of unidirectionally shadowed metal replicas of cyanide hydratase from Gloeocercospora sorghi. J Struct Biol. 2008 Feb;161(2):111-9. DOI:10.1016/j.jsb.2007.09.019 |
5. Sewell BT, Thuku RN, Zhang X, and Benedik MJ. Oligomeric structure of nitrilases: effect of mutating interfacial residues on activity. Ann N Y Acad Sci. 2005 Nov;1056:153-9. DOI:10.1196/annals.1352.025 |
6. Jandhyala DM, Willson RC, Sewell BT, and Benedik MJ. Comparison of cyanide-degrading nitrilases. Appl Microbiol Biotechnol. 2005 Aug;68(3):327-35. DOI:10.1007/s00253-005-1903-8 |
7. Strych U, Davlieva M, Longtin JP, Murphy EL, Im H, Benedik MJ, and Krause KL. Purification and preliminary crystallization of alanine racemase from Streptococcus pneumoniae. BMC Microbiol. 2007 May 17;7:40. DOI:10.1186/1471-2180-7-40 |
8. LeMagueres P, Im H, Ebalunode J, Strych U, Benedik MJ, Briggs JM, Kohn H, and Krause KL. The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site. Biochemistry. 2005 Feb 8;44(5):1471-81. DOI:10.1021/bi0486583 |
9. LeMagueres P, Im H, Ebalunode J, Strych U, Benedik MJ, Briggs JM, Kohn H, and Krause KL. The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site. Biochemistry. 2005 Feb 8;44(5):1471-81. DOI:10.1021/bi0486583 |
10. Jandhyala D, Berman M, Meyers PR, Sewell BT, Willson RC, and Benedik MJ. CynD, the cyanide dihydratase from Bacillus pumilus: gene cloning and structural studies. Appl Environ Microbiol. 2003 Aug;69(8):4794-805. DOI:10.1128/AEM.69.8.4794-4805.2003 |
11. Strych U and Benedik MJ. Mutant analysis shows that alanine racemases from Pseudomonas aeruginosa and Escherichia coli are dimeric. J Bacteriol. 2002 Aug;184(15):4321-5. DOI:10.1128/JB.184.15.4321-4325.2002 |

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