User:Matthew Whiteside/Notebook/Malaria Microarray/2009/09/11
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Mouse Malaria Microarray Datasets to Use in Meta-Analysis
Contrasts of InterestTo address the research question, i will look at two contrasts in gene expression:
Brain gene expression will be compared. Here late-stage is onset of CM symptoms around day 6 The following acronyms will be used:
StudiesOutlined below are the arrays that will be used to compute the contrasts (arrays classified as either CM, NCM or B) - UPDATE m2 and m3 were not carried forward, see Ref for explanation.
I have avoided custom cDNA arrays to keep things simple (its easier to annotate affy arrays). However in the future it may be necessary to include these too, in which case i would use the GEO array annotations. Analysis PlansWith the two contrasts, i am planning to peform two different analyses
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