User:Ilya/Yeast/Mating pheromone response pathway/Cdc28

• a Ser/Thr kinase

• Cdc28 is active when T169 is phosphorylated and T18 and Y19 are NOT phosphorylated (SwissProt).

The above statement was made by similarity arguments, though I have not found this statement anywhere in the literature.

• Ash1 is a potential substrate (restrict switching of mating types to mother cells)

• CKS1/YBR135W is a subunit of CDC28