Registry of Standard Biological Models/Basic Component Models/Constitutive Promoter

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Contents

Constitutive Promoter Architecture

  • Description: Promoter with constant transcription rate at a given number of gene copies
  • Hypothesis:
    • Constant and continuous transcription rate
    • Transcription rate depends on the number of gene copies
    • unlimited resources for transcription (excess in polymerase ...)
    • No effect from activators or repressors
  • Inputs:
    • nb-gene-copies
  • Outputs:
    • PoPs_out
  • Characteristic parameters:
    • transcription-rate-per-gene
Constitutive Promoter Brick Architecture
Constitutive Promoter Brick Architecture

CellML structure (CellML 1.1 spec)

  • Component: ConstitutivePromoter
  • Units:
    • TBD
  • Variables:
    • nbGeneCopies (public interface = in / init value = 1.0)
    • transcriptionRatePerGene (public interface = none / init value = XXX)
    • PoPs_OUT (public interface = out / init value = 0.)
  • MathML
    • amsmath


CellML File

<syntax type='xml'> <?xml version="1.0"?>

<model xmlns="http://www.cellml.org/cellml/1.0#"

      xmlns:cmeta="http://www.cellml.org/metadata/1.0#" 
      xml:base="file:///C:/CellML_models/constitutive_promoter.cml"
      cmeta:id="constitutive_promoter"
      name="constitutive_promoter">
 

<component name="constitutive_promoter">

<variable name="mRNAsynthesisRate" initial_value="" public_interface="out" units="moles_per_second"/> <variable name="nb_gene" initial_value="1" public_interface="none" units="dimensionless"/> <variable name="mRNAsynthesisRatePerGene" initial_value="1" public_interface="none" units="moles_per_second"/>

Failed to parse (Missing texvc executable; please see math/README to configure.): <apply id="mRNAsynthesisRate"> <eq/> <ci>mRNAsynthesisRate</ci> <apply> <times/> <ci>mRNAsynthesisRatePerGene</ci> <ci>nb_gene</ci> </apply> </apply>


</component>




<import xmlns:xlink="http://www.w3.org/1999/xlink"

       xlink:href="file://C:\CellML_models\units.cml">
     <units name="moles_per_second" units_ref="moles_per_second"/>
     <units name="per_second"       units_ref="per_second"/>

</import>




</model> </syntax>



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